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Chemiluminescence (Staining of MOLT4 lysate (35ug protein in RIPA buffer) using MBS646607 (0.5ug/ml). Primary incubation was 1 hour. Detected by chemiluminescence.)

Goat SOX11 Polyclonal Antibody

SOX11 (Transcription factor SOX-11)

Reactivity
Bovine, Human, Mouse, Porcine, Rat
Applications
ELISA, Western Blot
Purity
Affinity Purified
Purified by immunoaffinity chromatography.
Synonyms
SOX11; Polyclonal Antibody; SOX11 (Transcription factor SOX-11); Anti -SOX11 (Transcription factor SOX-11); anti-SOX11 antibody
Ordering
For Research Use Only!
Host
Goat
Reactivity
Bovine, Human, Mouse, Porcine, Rat
Clonality
Polyclonal
Specificity
Recognizes human SOX11. Species sequence homology: Mouse, rat, porcine and bovine.
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography.
Form/Format
Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
Applicable Applications for anti-SOX11 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes
Suitable for use in ELISA and Western Blot.
Dilution: ELISA: 1:2000
Western Blot: 0.3-1ug/ml, Daudi, Jurkat and MOLT4 cell lysates observed on ~65kD bands
Immunogen
Synthetic peptide corresponding to C-SRLYYSFKNITKQHP, from SOX11, at the internal region of the protein (NP_003099.1).
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Chemiluminescence

(Staining of MOLT4 lysate (35ug protein in RIPA buffer) using MBS646607 (0.5ug/ml). Primary incubation was 1 hour. Detected by chemiluminescence.)

Chemiluminescence (Staining of MOLT4 lysate (35ug protein in RIPA buffer) using MBS646607 (0.5ug/ml). Primary incubation was 1 hour. Detected by chemiluminescence.)
Related Product Information for anti-SOX11 antibody
The SOX (SRY-box containing gene) gene family encodes a group of transcription factors defined by the conserved high motility group (HMG) DNA-binding domain. They are involved in the regulation of embryonic development and in the determination of cell fate.
Product Categories/Family for anti-SOX11 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI Official Full Name
SOX11
Protein Family

Uniprot Description

SOX11: Probably important in the developing nervous system. May also have a role in tissue modeling during development.

Protein type: Transcription factor; DNA-binding

Chromosomal Location of Human Ortholog: 2p25

Cellular Component: cytoplasm; nucleus

Molecular Function: translation factor activity, nucleic acid binding; transcription factor activity

Biological Process: neural crest cell development; translation; positive regulation of transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; negative regulation of lymphocyte proliferation; glial cell proliferation; neuron differentiation; sympathetic nervous system development; regulation of transforming growth factor beta receptor signaling pathway; embryonic digestive tract morphogenesis; positive regulation of cell proliferation; hard palate development; kidney development; oligodendrocyte development; skeletal development; positive regulation of BMP signaling pathway; glial cell development; positive regulation of neurogenesis; transcription, DNA-dependent; positive regulation of hormone secretion; positive regulation of ossification; embryonic skeletal morphogenesis; positive regulation of osteoblast differentiation; limb bud formation; spinal cord development; lens morphogenesis in camera-type eye; positive regulation of transcription from RNA polymerase II promoter; soft palate development; positive regulation of neuron differentiation; neural tube formation

Disease: Mental Retardation, Autosomal Dominant 27

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Product Notes

The SOX11 (Catalog #AAA646607) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The SOX11 (Transcription factor SOX-11) reacts with Bovine, Human, Mouse, Porcine, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's SOX11 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB). Suitable for use in ELISA and Western Blot. Dilution: ELISA: 1:2000 Western Blot: 0.3-1ug/ml, Daudi, Jurkat and MOLT4 cell lysates observed on ~65kD bands. Researchers should empirically determine the suitability of the SOX11 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SOX11, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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