Western Blot (WB)
(SOX1 Antibody (N-term) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the SOX1 antibody detected the SOX1 protein (arrow).)
Rabbit SOX1 Polyclonal Antibody | anti-SOX1 antibody
SOX1 Antibody (N-term)
Western Blot (WB)
(SOX1 Antibody (N-term) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the SOX1 antibody detected the SOX1 protein (arrow).)
Western Blot (WB)
(SOX1 Antibody (N-term) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the SOX1 antibody detected the SOX1 protein (arrow).)
Flow Cytometry (FC/FACS)
(SOX1 Antibody (N-term) flow cytometric analysis of NCI-H460 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
Flow Cytometry (FC/FACS)
(SOX1 Antibody (N-term) flow cytometric analysis of NCI-H460 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
(SRY-related HMG-box) family of transcription factors involved in
the regulation of embryonic development and in the determination of
the cell fate. The encoded protein may act as a transcriptional
activator after forming a protein complex with other proteins. In
mice, a similar protein regulates the gamma-crystallin genes and is
essential for lens development.
Phi, J.H., et al. J Neurosurg Pediatr 5(6):608-614(2010)
Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010) :
Titulaer, M.J., et al. J. Clin. Oncol. 27(26):4260-4267(2009)
Stolk, L., et al. Nat. Genet. 41(6):645-647(2009)
NCBI and Uniprot Product Information
NCBI Description
This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. In mice, a similar protein regulates the gamma-crystallin genes and is essential for lens development. [provided by RefSeq, Jul 2008]
Uniprot Description
SOX1: Transcriptional activator. May function as a switch in neuronal development. Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation. Mainly expressed in the developing central nervous system.
Protein type: DNA-binding
Chromosomal Location of Human Ortholog: 13q34
Cellular Component: nucleus
Molecular Function: protein binding; DNA binding; transcription factor activity
Biological Process: establishment and/or maintenance of chromatin architecture; transcription, DNA-dependent; regulation of transcription, DNA-dependent; forebrain neuron development; neuron migration; lens morphogenesis in camera-type eye; ventral spinal cord interneuron specification
Research Articles on SOX1
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Product Notes
The SOX1 sox1 (Catalog #AAA9214656) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 47-76. The SOX1 Antibody (N-term) reacts with Human (Predicted Reactivity: Chicken, Zebrafish, Monkey, Mouse, Xenopus) and may cross-react with other species as described in the data sheet. AAA Biotech's SOX1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Flow Cytometry (FC/FACS). WB~~1:1000. Researchers should empirically determine the suitability of the SOX1 sox1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SOX1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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