Rabbit SOS1 Polyclonal Antibody | anti-SOS1 antibody

SOS1 Rabbit pAb

Cat. Num. AAA8543286

• Gene Names: SOS1; GF1; HGF; NS4; GGF1; GINGF; SOS-1
• Reactivity: Human, Mouse, Rat
• Applications: Western Blot, Immunohistochemistry, Immunocytochemistry, Immunofluorescence
• Purity: Affinity Chromatography
• Synonyms: SOS1; Polyclonal Antibody; SOS1 Rabbit pAb; alternate SOS1; GF1; GGF1; GINGF; gingival fibromatosis; HGF; NS4; Sos1; anti-SOS1 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Affinity Chromatography
• Form/Format: In phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% Sodium Azide and 50% Glycerol.
• Sequence Length: 1333

• Applicable Applications for anti-SOS1 antibody: Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
• Application Notes: WB: 1:500-1:2000; IHC: 1:50-1:200; ICC/IF: 1:50-1:200
• Immunogen: A synthesized peptide derived from human SOS1
• Preparation and Storage: Store at 4 degree C short term. Store at -20 degree C long term. Avoid freeze/thaw cycle.

Related Product Information for anti-SOS1 antibody

Promotes the exchange of Ras-bound GDP by GTP.

NCBI and Uniprot Product Information

• NCBI GI #: 15529996
• NCBI GeneID: 6654
• NCBI Accession #: NP_005624.2
• NCBI GenBank Nucleotide #: NP_005624.2
• UniProt Accession #: Q07889
• Molecular Weight: 152kDa
• NCBI Official Full Name: son of sevenless homolog 1
• NCBI Official Synonym Full Names: SOS Ras/Rac guanine nucleotide exchange factor 1
• NCBI Official Symbol: SOS1
• NCBI Official Synonym Symbols: GF1; HGF; NS4; GGF1; GINGF; SOS-1
• NCBI Protein Information: son of sevenless homolog 1
• UniProt Protein Name: Son of sevenless homolog 1
• Protein Family: Son of sevenless
• UniProt Gene Name: SOS1
• UniProt Synonym Gene Names: SOS-1
• UniProt Entry Name: SOS1_HUMAN

NCBI Description

This gene encodes a protein that is a guanine nucleotide exchange factor for RAS proteins, membrane proteins that bind guanine nucleotides and participate in signal transduction pathways. GTP binding activates and GTP hydrolysis inactivates RAS proteins. The product of this gene may regulate RAS proteins by facilitating the exchange of GTP for GDP. Mutations in this gene are associated with gingival fibromatosis 1 and Noonan syndrome type 4. [provided by RefSeq, Jul 2008]