Goat anti-Human SNX16 Polyclonal Antibody | anti-SNX16 antibody

SNX16, NT (Sorting Nexin 16, Sorting Nexin-16, DKFZp666H147)

Cat. Num. AAA6002416

• Reactivity: Human
• Applications: ELISA, Western Blot, Immunohistochemistry
• Purity: Affinity Purified; Purified by immunoaffinity chromatography.
• Synonyms: SNX16; Polyclonal Antibody; NT (Sorting Nexin 16; Sorting Nexin-16; DKFZp666H147); Anti -SNX16; anti-SNX16 antibody

• Host: Goat
• Reactivity: Human
• Clonality: Polyclonal
• Specificity: Recognizes human SNX16. Species sequence homology: Bovine, canine, mouse, rat.
• Purity/Purification: Affinity Purified; Purified by immunoaffinity chromatography.
• Form/Format: Supplied as a liquid in Tris saline buffer, pH 7.3, 0.5% BSA, 0.02% sodium azide.

• Applicable Applications for anti-SNX16 antibody: ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
• Application Notes: Suitable for use in ELISA, Western Blot and Immunohistochemistry.; Dilution: ELISA: 1:64,000; Western Blot: 1:64,000 & 0.05-0.2ug/ml; Immunohistochemistry (Formalin fixed paraffin embedded): 3.75ug/ml
• Immunogen: Synthetic peptide corresponding to ATPYVPVPMPIGN-C of human SNX16 at N-terminal.
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Immunohistochemistry (IHC)

(Human Breast: Formalin-Fixed, Paraffin-Embedded (FFPE))

Immunohistochemistry (IHC)

(Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE))

Immunohistochemistry (IHC)

(Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE))

Testing Data

(Antibody (0.05ug/ml) staining of Daudi lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)

Related Product Information for anti-SNX16 antibody

This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. The function of this protein has not been determined. This gene results in three transcript variants encoding two distinct isoforms.

Product Categories/Family for anti-SNX16 antibody

Antibodies; Abs to SNX (Sorting Nexin) Proteins

NCBI and Uniprot Product Information

• NCBI GI #: 23238246
• NCBI GeneID: 64089
• NCBI Accession #: NP_690049.1
• NCBI GenBank Nucleotide #: NM_152836.2
• UniProt Accession #: P57768; Q658L0; Q8N4U3; A8K4D8
• Molecular Weight: 39,167 Da
• NCBI Official Full Name: sorting nexin-16 isoform a
• NCBI Official Synonym Full Names: sorting nexin 16
• NCBI Official Symbol: SNX16
• NCBI Protein Information: sorting nexin-16
• UniProt Protein Name: Sorting nexin-16
• Protein Family: Sorting nexin
• UniProt Gene Name: SNX16
• UniProt Entry Name: SNX16_HUMAN

NCBI Description

This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. The function of this protein has not been determined. This gene results in three transcript variants encoding two distinct isoforms. [provided by RefSeq, Jul 2008]

Uniprot Description

SNX16: May be involved in several stages of intracellular trafficking. Plays a role in protein transport from early to late endosomes. Plays a role in protein transport to the lysosome. Promotes degradation of EGFR after EGF signaling. Plays a role in intracellular transport of vesicular stomatitis virus nucleocapsids from the endosome to the cytoplasm. Belongs to the sorting nexin family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Vesicle

Chromosomal Location of Human Ortholog: 8q21.13

Cellular Component: late endosome membrane; lysosome; early endosome membrane; late endosome; early endosome

Molecular Function: identical protein binding; phosphoinositide binding

Biological Process: protein targeting to lysosome; early endosome to late endosome transport; endosome to lysosome transport