Rabbit anti-Human, Mouse SNRPB Polyclonal Antibody | anti-SNRPB antibody

SNRPB Polyclonal Antibody

Cat. Num. AAA9130361

• Gene Names: SNRPB; COD; CCMS; SNRPB1; SmB/B'; Sm-B/B'; snRNP-B; SmB/SmB'
• Reactivity: Human, Mouse
• Applications: Western Blot, Immunohistochemistry
• Purity: Affinity purification
• Synonyms: SNRPB; Polyclonal Antibody; SNRPB Polyclonal Antibody ; COD; CCMS; SNRPB1; SmB/B'; Sm-B/B'; snRNP-B; SmB/SmB'; anti-SNRPB antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Affinity purification
• Sequence Length: 231

• Applicable Applications for anti-SNRPB antibody: Western Blot (WB), Immunohistochemistry (IHC)
• Application Notes: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200
• Immunogen: Recombinant protein of human SNRPB
• Preparation and Storage: Store at -20 degree C. Avoid freeze / thaw cycles.

Western Blot (WB)

(Western blot analysis of extracts of various cell lines, using SNRPB antibody at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit.Exposure time: 180s.)

Related Product Information for anti-SNRPB antibody

The protein encoded by this gene is one of several nuclear proteins that are found in common among U1, U2, U4/U6, and U5 small ribonucleoprotein particles (snRNPs). These snRNPs are involved in pre-mRNA splicing, and the encoded protein may also play a role in pre-mRNA splicing or snRNP structure. Autoantibodies from patients with systemic lupus erythematosus frequently recognize epitopes on the encoded protein. Two transcript variants encoding different isoforms (B and B') have been found for this gene.

Product Categories/Family for anti-SNRPB antibody

Polyclonal

NCBI and Uniprot Product Information

• NCBI GI #: 4507125
• NCBI GeneID: 6628
• NCBI Accession #: NP_003082.1
• NCBI GenBank Nucleotide #: NM_003091.3
• UniProt Accession #: P14678; Q15490; Q6IB35; Q9UIS5
• Molecular Weight: Calculated MW: 25kDa; Molecular Weight: 240
• NCBI Official Full Name: small nuclear ribonucleoprotein-associated proteins B and B' isoform B
• NCBI Official Synonym Full Names: small nuclear ribonucleoprotein polypeptides B and B1
• NCBI Official Symbol: SNRPB
• NCBI Official Synonym Symbols: COD; CCMS; SNRPB1; SmB/B'; Sm-B/B'; snRNP-B; SmB/SmB'
• NCBI Protein Information: small nuclear ribonucleoprotein-associated proteins B and B'
• UniProt Protein Name: Small nuclear ribonucleoprotein-associated proteins B and B'
• Protein Family: Small nuclear ribonucleoprotein-associated protein
• UniProt Gene Name: SNRPB
• UniProt Synonym Gene Names: COD; SNRPB1; snRNP-B; Sm-B/B'; SmB/B'
• UniProt Entry Name: RSMB_HUMAN

NCBI Description

The protein encoded by this gene is one of several nuclear proteins that are found in common among U1, U2, U4/U6, and U5 small ribonucleoprotein particles (snRNPs). These snRNPs are involved in pre-mRNA splicing, and the encoded protein may also play a role in pre-mRNA splicing or snRNP structure. Autoantibodies from patients with systemic lupus erythematosus frequently recognize epitopes on the encoded protein. Two transcript variants encoding different isoforms (B and B') have been found for this gene. [provided by RefSeq, Jul 2008]

Uniprot Description

Core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. As part of the U7 snRNP it is involved in histone 3'-end processing.