Loading...

Skip to main content

Call us on + 1 (800) 604-9114 for more information about our products

Looking for specific datasheet Manual/COA/MSDS?
Request a Manual/COA/MSDS

Interested to get a quote about our products?
Request a Quote

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded rat brain using ZNF346 antibody at dilution of 1:100 .)

Rabbit ZNF346 Polyclonal Antibody | anti-ZNF346 antibody

ZNF346 Polyclonal Antibody

Gene Names
ZNF346; JAZ; Zfp346
Reactivity
Human, Mouse, Rat
Applications
Western Blot, Immunohistochemistry, Immunofluorescence
Purity
Affinity purification
Synonyms
ZNF346; Polyclonal Antibody; ZNF346 Polyclonal Antibody; JAZ; Zfp346; anti-ZNF346 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity purification
Form/Format
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH7.4, 150mM NaCl, 0.02% sodium azide and 316% glycerol.
PBS with 0.02% sodium azide, 50% glycerol, pH7.269
Concentration
1mg/ml (varies by lot)
Applicable Applications for anti-ZNF346 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes
WB: 1:500-1:2000
IHC: 1:50-1:200
IF: 1:50-1:200
Immunogen
Recombinant fusion protein of human ZNF346 (NP_036411.1)
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded rat brain using ZNF346 antibody at dilution of 1:100 .)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded rat brain using ZNF346 antibody at dilution of 1:100 .)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human tonsil using ZNF346 antibody at dilution of 1:100 .)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human tonsil using ZNF346 antibody at dilution of 1:100 .)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human lung cancer using ZNF346 antibody at dilution of 1:100 .)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human lung cancer using ZNF346 antibody at dilution of 1:100 .)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human appendix using ZNF346 antibody at dilution of 1:100 .)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human appendix using ZNF346 antibody at dilution of 1:100 .)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded mouse brain using ZNF346 antibody at dilution of 1:100 .)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded mouse brain using ZNF346 antibody at dilution of 1:100 .)

Immunofluorescence (IF)

(Immunofluorescence analysis of NIH/3T3 cells using ZNF346 antibody at dilution of 1:100. Blue: DAPI for nuclear staining.)

Immunofluorescence (IF) (Immunofluorescence analysis of NIH/3T3 cells using ZNF346 antibody at dilution of 1:100. Blue: DAPI for nuclear staining.)

Immunofluorescence (IF)

(Immunofluorescence analysis of U2OS cells using ZNF346 antibody at dilution of 1:100. Blue: DAPI for nuclear staining.)

Immunofluorescence (IF) (Immunofluorescence analysis of U2OS cells using ZNF346 antibody at dilution of 1:100. Blue: DAPI for nuclear staining.)

Western Blot (WB)

(Western blot analysis of extracts of various cell lines, using ZNF346 antibody at 1:1000 dilution.)

Western Blot (WB) (Western blot analysis of extracts of various cell lines, using ZNF346 antibody at 1:1000 dilution.)
Related Product Information for anti-ZNF346 antibody
The protein encoded by this gene is a nucleolar, zinc finger protein that preferentially binds to double-stranded (ds) RNA or RNA/DNA hybrids, rather than DNA alone. Mutational studies indicate that the zinc finger domains are not only essential for dsRNA binding, but are also required for its nucleolar localization. The encoded protein may be involved in cell growth and survival. It plays a role in protecting neurons by inhibiting cell cycle re-entry via stimulation of p21 gene expression. Alternative splicing of this gene results in multiple transcript variants.
Product Categories/Family for anti-ZNF346 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
29,267 Da
NCBI Official Full Name
zinc finger protein 346
NCBI Official Synonym Full Names
zinc finger protein 346
NCBI Official Symbol
ZNF346
NCBI Official Synonym Symbols
JAZ; Zfp346
NCBI Protein Information
zinc finger protein 346; double-stranded RNA-binding zinc finger protein JAZ; just another zinc finger protein
UniProt Protein Name
Zinc finger protein 346
Protein Family
UniProt Gene Name
ZNF346
UniProt Synonym Gene Names
JAZ
UniProt Entry Name
ZN346_HUMAN

NCBI Description

The protein encoded by this gene is a nucleolar, zinc finger protein that preferentially binds to double-stranded (ds) RNA or RNA/DNA hybrids, rather than DNA alone. Mutational studies indicate that the zinc finger domains are not only essential for dsRNA binding, but are also required for its nucleolar localization. The encoded protein may be involved in cell growth and survival. [provided by RefSeq, Jul 2008]

Uniprot Description

ZNF346: Binds to dsRNA and DNA. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Nucleolus

Chromosomal Location of Human Ortholog: 5q35.2

Cellular Component: nucleoplasm; cytoplasm; nucleolus; nucleus

Molecular Function: protein binding; enzyme binding; zinc ion binding; double-stranded RNA binding

Biological Process: positive regulation of apoptosis

Research Articles on ZNF346

Similar Products

Product Notes

The ZNF346 znf346 (Catalog #AAA9457657) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ZNF346 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's ZNF346 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF). WB: 1:500-1:2000 IHC: 1:50-1:200 IF: 1:50-1:200. Researchers should empirically determine the suitability of the ZNF346 znf346 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ZNF346, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

Item has been added to Shopping Cart

If you are ready to order, navigate to Shopping Cart and get ready to checkout.

Looking for a specific manual?
Request a Manual

Request more Information

Please complete the form below and a representative will contact you as soon as possible.

Request a Manual

Please complete the form below and a representative will contact you as soon as possible.

Request a Quote

Please complete the form below and a representative will contact you as soon as possible.