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Western Blot (WB) (Western Blot analysis of Human placenta tissue and hela cell, hepg2 cell and Human fetal liver tissue, A549 cell and Human normal kidney tissue using SNAP23 Polyclonal Antibody at dilution of 1:400)

Rabbit SNAP23 Polyclonal Antibody | anti-SNAP23 antibody

SNAP23 Polyclonal Antibody

Gene Names
SNAP23; SNAP-23; SNAP23A; SNAP23B; HsT17016
Reactivity
Human, Mouse, Rat
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Antigen affinity purification
Synonyms
SNAP23; Polyclonal Antibody; SNAP23 Polyclonal Antibody; SNAP-23; SNAP23A; SNAP23B; HsT17016; anti-SNAP23 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen affinity purification
Concentration
1.4mg/mL (varies by lot)
Sequence Length
158
Applicable Applications for anti-SNAP23 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
WB: 1:500-1:2000
IHC: 1:25-1:100
Immunogen
Recombinant protein of human SNAP23
Buffer
PBS with 0.05% sodium azide, 50% glycerol, pH7.3
Preparation and Storage
Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.

Western Blot (WB)

(Western Blot analysis of Human placenta tissue and hela cell, hepg2 cell and Human fetal liver tissue, A549 cell and Human normal kidney tissue using SNAP23 Polyclonal Antibody at dilution of 1:400)

Western Blot (WB) (Western Blot analysis of Human placenta tissue and hela cell, hepg2 cell and Human fetal liver tissue, A549 cell and Human normal kidney tissue using SNAP23 Polyclonal Antibody at dilution of 1:400)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Human prostate cancer using SNAP23 Polyclonal Antibody at dilution of 1:25)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human prostate cancer using SNAP23 Polyclonal Antibody at dilution of 1:25)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Human breast cancer using SNAP23 Polyclonal Antibody at dilution of 1:25)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human breast cancer using SNAP23 Polyclonal Antibody at dilution of 1:25)
Related Product Information for anti-SNAP23 antibody
Specificity of vesicular transport is regulated, in part, by the interaction of a vesicle-associated membrane protein termed synaptobrevin/VAMP with a target compartment membrane protein termed syntaxin. These proteins, together with SNAP25 (synaptosome-associated protein of 25 kDa), form a complex which serves as a binding site for the general membrane fusion machinery.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
17,789 Da
NCBI Official Full Name
synaptosomal-associated protein 23 isoform SNAP23B
NCBI Official Synonym Full Names
synaptosomal-associated protein, 23kDa
NCBI Official Symbol
SNAP23
NCBI Official Synonym Symbols
SNAP-23; SNAP23A; SNAP23B; HsT17016
NCBI Protein Information
synaptosomal-associated protein 23; synaptosomal-associated protein, 23kD; vesicle-membrane fusion protein SNAP-23
UniProt Protein Name
Synaptosomal-associated protein 23
UniProt Gene Name
SNAP23
UniProt Synonym Gene Names
SNAP-23
UniProt Entry Name
SNP23_HUMAN

NCBI Description

Specificity of vesicular transport is regulated, in part, by the interaction of a vesicle-associated membrane protein termed synaptobrevin/VAMP with a target compartment membrane protein termed syntaxin. These proteins, together with SNAP25 (synaptosome-associated protein of 25 kDa), form a complex which serves as a binding site for the general membrane fusion machinery. Synaptobrevin/VAMP and syntaxin are believed to be involved in vesicular transport in most, if not all cells, while SNAP25 is present almost exclusively in the brain, suggesting that a ubiquitously expressed homolog of SNAP25 exists to facilitate transport vesicle/target membrane fusion in other tissues. The protein encoded by this gene is structurally and functionally similar to SNAP25 and binds tightly to multiple syntaxins and synaptobrevins/VAMPs. It is an essential component of the high affinity receptor for the general membrane fusion machinery and is an important regulator of transport vesicle docking and fusion. Two alternative transcript variants encoding different protein isoforms have been described for this gene. [provided by RefSeq, Jul 2008]

Uniprot Description

SNAP23: a member of the SNAP-25 family of SNARE proteins. Structurally and functionally similar to SNAP25 and binds tightly to multiple syntaxins and synaptobrevins/VAMPs. It is an essential component of the high affinity receptor for the general membrane fusion machinery and is an important regulator of transport vesicle docking and fusion. Two alternatively spliced isoforms have been described.

Protein type: Vesicle

Chromosomal Location of Human Ortholog: 15q14

Cellular Component: nucleoplasm; SNARE complex; azurophil granule; specific granule; neuron projection; mast cell granule; focal adhesion; cytoplasm; plasma membrane; synapse

Molecular Function: SNAP receptor activity; protein binding; syntaxin binding

Biological Process: synaptic vesicle fusion to presynaptic membrane; protein transport; histamine secretion by mast cell; vesicle targeting; post-Golgi vesicle-mediated transport; synaptic vesicle priming

Research Articles on SNAP23

Similar Products

Product Notes

The SNAP23 snap23 (Catalog #AAA2524648) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SNAP23 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's SNAP23 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). WB: 1:500-1:2000 IHC: 1:25-1:100. Researchers should empirically determine the suitability of the SNAP23 snap23 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SNAP23, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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