Immunohistochemistry (IHC)
(Human Brain, Cortex (formalin-fixed, paraffin-embedded) stained with SMOC2 antibody at 20ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody alkaline phosphatase-streptavidin and chromogen.)
Rabbit anti-Human SMOC2 Polyclonal Antibody | anti-SMOC2 antibody
SMOC2, NT (SPARC-related Modular Calcium-binding Protein 2, Secreted Modular Calcium-binding Protein 2, SMOC-2, Smooth Muscle-associated Protein 2, SMAP-2, SMAP2, MSTP117)
Purified by immunoaffinity chromatography.
Purified by immunoaffinity chromatography.
Dilution: ELISA: 1ug/ml
Western Blot: 1ug/ml
Immunohistochemistry (Formalin fixed paraffin embedded): 20ug/ml
Immunohistochemistry (IHC)
(Human Brain, Cortex (formalin-fixed, paraffin-embedded) stained with SMOC2 antibody at 20ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody alkaline phosphatase-streptavidin and chromogen.)
Immunohistochemistry (IHC)
(Human Brain, Cortex (formalin-fixed, paraffin-embedded) stained with SMOC2 antibody at 20ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody alkaline phosphatase-streptavidin and chromogen.)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the SPARC family (secreted protein acidic and rich in cysteine/osteonectin/BM-40), which are highly expressed during embryogenesis and wound healing. The gene product is a matricellular protein which promotes matrix assembly and can stimulate endothelial cell proliferation and migration, as well as angiogenic activity. Associated with pulmonary function, this secretory gene product contains a Kazal domain, two thymoglobulin type-1 domains, and two EF-hand calcium-binding domains. The encoded protein may serve as a target for controlling angiogenesis in tumor growth and myocardial ischemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
Uniprot Description
SMOC2: Promotes matrix assembly and cell adhesiveness. Can stimulate endothelial cell proliferation, migration, as well as angiogenesis. Defects in SMOC2 are the cause of dentin dysplasia typ1 (DTDP1). A dental defect in which both primary and secondary dentitions are affected. The clinical crowns of both permanent and deciduous teeth are of normal shape, form and color in most cases, although they may be slightly opalescent and blue or brown. Teeth may be very mobile and exfoliate spontaneously because of inadequate root formation. On radiographs, the roots are short and may be more pointed than normal. Pulp chambers are usually absent except for a chevron-shaped remnant in the crown. Root canals are usually absent. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Secreted; Secreted, signal peptide; Calcium-binding
Chromosomal Location of Human Ortholog: 6q27
Cellular Component: basement membrane
Molecular Function: heparin binding; calcium ion binding
Biological Process: extracellular matrix organization and biogenesis; signal transduction
Disease: Dentin Dysplasia, Type I
Research Articles on SMOC2
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Product Notes
The SMOC2 smoc2 (Catalog #AAA6001559) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SMOC2, NT (SPARC-related Modular Calcium-binding Protein 2, Secreted Modular Calcium-binding Protein 2, SMOC-2, Smooth Muscle-associated Protein 2, SMAP-2, SMAP2, MSTP117) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SMOC2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC). Suitable for use in ELISA, Western Blot and Immunohistochemistry. Dilution: ELISA: 1ug/ml Western Blot: 1ug/ml Immunohistochemistry (Formalin fixed paraffin embedded): 20ug/ml. Researchers should empirically determine the suitability of the SMOC2 smoc2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SMOC2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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