Western Blot (WB)
(Western blot analysis of SMCHD1 expression in 293T cell lysate.)
Rabbit anti-Human SMCHD1 Polyclonal Antibody | anti-SMCHD1 antibody
SMCHD1 Rabbit pAb
Reactivity
Human
Applications
Western Blot, Immunohistochemistry
Purity
Affinity purified
Synonyms
SMCHD1; Polyclonal Antibody; SMCHD1 Rabbit pAb; BAMS; FSHD2; Smchd1; anti-SMCHD1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
SMCHD1 Antibody detects endogenous levels of total SMCHD1
Purity/Purification
Affinity purified
Form/Format
Rabbit IgG in phosphate buffered saline, pH7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Applicable Applications for anti-SMCHD1 antibody
Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P)
Application Notes
WB: 1:500-1:2000
IHC: 1:50-1:200
IHC: 1:50-1:200
Immunogen
A synthesized peptide derived from human SMCHD1
Conjugation
Unconjugated
Modification
Unmodified
Preparation and Storage
Store at +4 degree C for short term. Store at -20 degree C for long term. Avoid freeze/thaw cycle.
Western Blot (WB)
(Western blot analysis of SMCHD1 expression in 293T cell lysate.)
Western Blot (WB)
(Western blot analysis of SMCHD1 expression in 293T cell lysate.)
Related Product Information for anti-SMCHD1 antibody
Required for maintenance of X inactivation in females and hypermethylation of CpG islands associated with inactive X. Involved in a pathway that mediates the methylation of a subset of CpG islands slowly and requires the methyltransferase DNMT3B (By similarity). Required for DUX4 silencing in somatic cells.
Product Categories/Family for anti-SMCHD1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
226,374 Da
NCBI Official Full Name
structural maintenance of chromosomes flexible hinge domain-containing protein 1
NCBI Official Synonym Full Names
structural maintenance of chromosomes flexible hinge domain containing 1
NCBI Official Symbol
SMCHD1
NCBI Protein Information
structural maintenance of chromosomes flexible hinge domain-containing protein 1; SMC hinge domain-containing protein 1
UniProt Protein Name
Structural maintenance of chromosomes flexible hinge domain-containing protein 1
UniProt Gene Name
SMCHD1
UniProt Synonym Gene Names
KIAA0650
UniProt Entry Name
SMHD1_HUMAN
NCBI Description
This gene encodes a protein which contains a hinge region domain found in members of the SMC (structural maintenance of chromosomes) protein family. [provided by RefSeq, Dec 2011]
Uniprot Description
SMCHD1: Required for maintenance of X inactivation in females and hypermethylation of CpG islands associated with inactive X. Involved in a pathway that mediates the methylation of a subset of CpG islands slowly and requires the de novo methyltransferase DNMT3B. 3 isoforms of the human protein are produced by alternative splicing.
Chromosomal Location of Human Ortholog: 18p11.32
Cellular Component: Barr body
Molecular Function: ATP binding
Biological Process: chromosome organization and biogenesis
Disease: Facioscapulohumeral Muscular Dystrophy 2
Research Articles on SMCHD1
Similar Products
Product Notes
The SMCHD1 smchd1 (Catalog #AAA4757364) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SMCHD1 Rabbit pAb reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SMCHD1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P). WB: 1:500-1:2000 IHC: 1:50-1:200. Researchers should empirically determine the suitability of the SMCHD1 smchd1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SMCHD1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
