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Rabbit Smad1 Polyclonal Antibody | anti-Smad1 antibody

Smad1 Antibody FITC-Conjugated

Gene Names
Mad; 2/23; apg; c28; CG12399; dMad; dMAD; DmelCG12399; E(zen)2; En(vvl); l(2)k00237; l(2)K00237; mad; MAD; Mat; p-Mad; P-mad; P-Mad; pMad; pMAD; PMad; pSmad; Smad; Smad1
Reactivity
Drosophila melanogaster
Applications
ELISA, Western Blot
Synonyms
Smad1; Polyclonal Antibody; Smad1 Antibody FITC-Conjugated; BSP 1; Dwarfin A; DwfA; JV 41; MAD homolog 1; MAD mothers against decapentaplegic homolog 1; Mad related protein 1; MADR1; Mothers against DPP homolog 1; Sma and Mad related protein 1; SMAD 1; Spinal muscular atrophy distal with upper limb predominance; TGF beta signaling protein 1; Transforming growth factor beta signaling protein 1 antibody; anti-Smad1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Drosophila melanogaster
Clonality
Polyclonal
Form/Format
FITC-Conjugated
Concentration
0.5-1.0 ug/ul in antibody stabilization buffer (varies by lot)
Sequence Length
455
Applicable Applications for anti-Smad1 antibody
ELISA (EIA), IMM, Western Blot (WB)
Application Notes
Dot Blot: 1:20,000-1:50,000
ELISA: 1:20,000-1:50,000
Immunoprecipitation: 1:200
Western Blot: 1:500
Immunogen
Synthetic peptide taken within amino acid region 405-455 on D. melanogaster Mothers against dpp protein.
Expression
Is detected in all developmental stages, though it appears most abundant in pupae, adult stages and early embryos. Its abundance decreases throughout embryonic and larval development and then returns to high levels in pupae and adult females.
Molecular Function
DNA binding; RNA polymerase II activating transcription factor; Transcription regulatory region sequence-specific activity; Transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity
Structure
Homotrimer
Subcellular Location
Cytoplasm; Nucleus
Preparation and Storage
-20 degree C for long term storage
Related Product Information for anti-Smad1 antibody
FITC-Conjugated Mothers against dpp Antibody
Required for the function of decapentaplegic. May play an important role in mediating Dpp signaling. Involved in the BMP signaling pathway.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
50,505 Da
NCBI Official Full Name
mothers against dpp, isoform A
NCBI Official Synonym Full Names
Mothers against dpp
NCBI Official Symbol
Mad
NCBI Official Synonym Symbols
2/23; apg; c28; CG12399; dMad; dMAD; DmelCG12399; E(zen)2; En(vvl); l(2)k00237; l(2)K00237; mad; MAD; Mat; p-Mad; P-mad; P-Mad; pMad; pMAD; PMad; pSmad; Smad; Smad1
NCBI Protein Information
CG12399 gene product from transcript CG12399-RB
UniProt Protein Name
Protein mothers against dpp
UniProt Gene Name
Mad
UniProt Entry Name
MAD_DROME

Uniprot Description

Required for the function of decapentaplegic. May play an important role in mediating Dpp signaling. Involved in the BMP signaling pathway.

Research Articles on Smad1

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Product Notes

The Smad1 mad (Catalog #AAA542019) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Smad1 Antibody FITC-Conjugated reacts with Drosophila melanogaster and may cross-react with other species as described in the data sheet. AAA Biotech's Smad1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), IMM, Western Blot (WB). Dot Blot: 1:20,000-1:50,000 ELISA: 1:20,000-1:50,000 Immunoprecipitation: 1:200 Western Blot: 1:500. Researchers should empirically determine the suitability of the Smad1 mad for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Smad1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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