Western Blot (WB)
(Western blot analysis of SLPI in A-20 cell lysate with SLPI antibody at 2 ug/mL.)
Rabbit anti-Mouse SLPI Polyclonal Antibody | anti-SLPI antibody
SLPI Antibody
Reactivity
Mouse
Applications
ELISA, Western Blot
Purity
Affinity chromatography purified via peptide column
Synonyms
SLPI; Polyclonal Antibody; SLPI Antibody; mSLPI; Secretory leukocyte protease inhibitor; HUSI; anti-SLPI antibody
Host
Rabbit
Reactivity
Mouse
Clonality
Polyclonal
Purity/Purification
Affinity chromatography purified via peptide column
Form/Format
Supplied in PBS containing 0.02% sodium azide.
Concentration
1mg/ml (varies by lot)
Sequence Length
131
Applicable Applications for anti-SLPI antibody
ELISA (EIA), Western Blot (WB)
Immunogen Type
Peptide
Immunogen Description
Raised against a 17 amino acid peptide from near the center of mouse SLPI.
Target Name
SLPI
Preparation and Storage
Can be stored at -20°C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Western Blot (WB)
(Western blot analysis of SLPI in A-20 cell lysate with SLPI antibody at 2 ug/mL.)
Western Blot (WB)
(Western blot analysis of SLPI in A-20 cell lysate with SLPI antibody at 2 ug/mL.)
Related Product Information for anti-SLPI antibody
Secretory leukocyte protease inhibitor (SLPI) is produced at mucosal surfaces, primarily the upper respiratory tract and is thought to play an important role in the antiprotease defense mechanism of the lung. SLPI forms inhibitory complexes with numerous proteolytic enzymes such as neutrophil elastase, and has been shown to possess anti-inflammatory, anti-viral, and antibacterial activities. Its expression in oral epithelial cells is stimulated by HIV-1 gp120, suggesting that SLPI is a component of the oral mucosal response to HIV-1. In peripheral blood monocytes, SLPI can inhibit NF-kB activation by inhibiting IkB degradation in the cytoplasm and competing for NF-kB binding sites in the nucleus. This attenuation of the inflammatory response may also act to suppress liver metastases and other cancer cell invasions, but promote blood-borne metastasis via an invasion-independent pathway.
Product Categories/Family for anti-SLPI antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
antileukoproteinase
NCBI Official Synonym Full Names
secretory leukocyte peptidase inhibitor
NCBI Official Symbol
Slpi
NCBI Protein Information
antileukoproteinase
UniProt Protein Name
Antileukoproteinase
Protein Family
UniProt Gene Name
Slpi
UniProt Synonym Gene Names
ALP
UniProt Entry Name
SLPI_MOUSE
Uniprot Description
SLPI: Acid-stable proteinase inhibitor with strong affinities for trypsin, chymotrypsin, elastase, and cathepsin G. May prevent elastase-mediated damage to oral and possibly other mucosal tissues.
Protein type: Inhibitor; Secreted; Secreted, signal peptide
Cellular Component: extracellular matrix; extracellular region
Molecular Function: serine-type endopeptidase inhibitor activity; enzyme binding; protease inhibitor activity; endopeptidase inhibitor activity
Biological Process: negative regulation of viral genome replication; negative regulation of peptidase activity; negative regulation of protein binding
Research Articles on SLPI
Similar Products
Product Notes
The SLPI slpi (Catalog #AAA9408899) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SLPI Antibody reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's SLPI can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). Researchers should empirically determine the suitability of the SLPI slpi for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SLPI, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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