Rabbit anti-Human SLP-76 Polyclonal Antibody | anti-SLP-76 antibody

SLP-76 (SH2 Domain Containing Leukocyte Protein 76kD, SH2 Domain-containing Leukocyte Protein of 76kD, SH2 Domain Containing Leukocyte Protein of 76kDa, SLP76, SLP76 Tyrosine Phosphoprotein, SLP-76 Tyrosine Phosphoprotein, 76kD Tyrosine Phosphoprotein, Ly

Cat. Num. AAA6394398

• Gene Names: LCP2; SLP76; SLP-76
• Reactivity: Human
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: SLP-76; Polyclonal Antibody; SLP-76 (SH2 Domain Containing Leukocyte Protein 76kD; SH2 Domain-containing Leukocyte Protein of 76kD; SH2 Domain Containing Leukocyte Protein of 76kDa; SLP76; SLP76 Tyrosine Phosphoprotein; SLP-76 Tyrosine Phosphoprotein; 76kD Tyrosine Phosphoprotein; Ly; anti-SLP-76 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human LCP2.
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).
• Sequence Length: 533

• Applicable Applications for anti-SLP-76 antibody: Western Blot (WB)
• Application Notes: Applications are based on unconjugated antibody.
• Immunogen: Full length human LCP2, aa1-533 (AAH16618.1).
• Immunogen Sequence: MALRNVPFRSEVLGWDPDSLADYFKKLNYKDCEKAVKKYHIDGARFLNLTENDIQKFPKLRVPILSKLSQEINKNEERRSIFTRKPQVPRFPEETESHEEDNGGWSSFEEDDYESPNDDQDGEDDGDYESPNEEEEAPVEDDADYEPPPSNDEEALQNSILPAKPFPNSNSMYIDRPPSGKTPQQPPVPPQRPMAALPPPPAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTKPPLDRSLAPFDREPFTLGKKPPFSDKPSIPAGRSLGEHLPKIQKPPLPPTTERHERSSPLPGKKPPVPKHGWGPDRRENDEDDVHQRPLPQPALLPMSSNTFPSRSTKPSPMNPLPSSHMPGAFSESNSSFPQSASLPPYFSQGPSNRPPIRAEGRNFPLPLPNKPRPPSPAEEENSLNEEWYVSYITRPEAEAALRKINQDGTFLVRDSSKKTTTNPYVLMVLYKDKVYNIQIRYQKESQVYLLGTGLRGKEDFLSVSDIIDYFRKMPLLLIDGKNRGSRYQCTLTHAAGYP
• Conjugate: PE
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(Western Blot analysis of LCP2 expression in transfected 293T cell line by LCP2 polyclonal antibody. Lane 1: LCP2 transfected lysate (60.2kD). Lane 2: Non-transfected lysate.)

Related Product Information for anti-SLP-76 antibody

SLP-76 (SH2 domain-containing leukocyte protein) is a 76kD cytosolic adaptor molecule that is involved in T cell development and activation.

Product Categories/Family for anti-SLP-76 antibody

Antibodies; T Cells

NCBI and Uniprot Product Information

• NCBI GI #: 16741630
• NCBI GeneID: 3937
• NCBI Accession #: AAH16618.1
• NCBI GenBank Nucleotide #: NM_005565
• NCBI Official Full Name: Lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
• NCBI Official Synonym Full Names: lymphocyte cytosolic protein 2
• NCBI Official Symbol: LCP2
• NCBI Official Synonym Symbols: SLP76; SLP-76
• NCBI Protein Information: lymphocyte cytosolic protein 2

NCBI Description

This gene encodes an adapter protein that acts as a substrate of the T cell antigen receptor (TCR)-activated protein tyrosine kinase pathway. The encoded protein associates with growth factor receptor bound protein 2, and is thought to play a role TCR-mediated intracellular signal transduction. A similar protein in mouse plays a role in normal T-cell development and activation. Mice lacking this gene show subcutaneous and intraperitoneal fetal hemorrhaging, dysfunctional platelets and impaired viability. [provided by RefSeq, Nov 2016]