Rabbit SLCO3A1 Polyclonal Antibody | anti-SLCO3A1 antibody
SLCO3A1 Antibody
Gene Names
SLCO3A1; OATPD; OATP-D; OATP3A1; SLC21A11
Reactivity
Human, Mouse, Rat
Applications
ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Synonyms
SLCO3A1; Polyclonal Antibody; SLCO3A1 Antibody; FLJ40478; OATP D; OATP RP3; OATP3A1; OATPD; OATPRP3; Organic anion transporter polypeptide related protein 3; Organic anion transporting polypeptide D; PGE1 transporter; SLC21A11; Sodium independent organic anion transporter D; Solute carrier family 21 (organic anion transporter) member 11; Solute carrier family 21 member 11; Solute carrier organic anion transporter family member 3A1; anti-SLCO3A1 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
SLCO3A1 Antibody detects endogenous levels of SLCO3A1.
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Form/Format
Liquid. Rabbit IgG in phosphate buffered saline, pH7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Applicable Applications for anti-SLCO3A1 antibody
ELISA (EIA)(peptide)
Application Notes
ELISA(peptide): 1:20000-1:40000
Immunogen
A synthesized peptide derived from human SLCO3A1.
Conjugation
Unconjugated
Similarity
Belongs to the organo anion transporter (TC 2. A. 60) family.
Tissue Specificity
Ubiquitous. Highly expressed in spleen and leukocytes. Generally the expression of isoform 1 is higher than that of isoform 2. Isoform 2 is particularly abundant in testis and brain. In testis, isoform 1 is detected in spermatogonia at different stages and absent from Sertoli cells, while isoform 2 is present in both (at protein level). Expressed in the choroid plexus epithelium, isoform 1 being localized at the basolateral membrane and isoform 2 at the apical one, as well as in the subapical intracellular vesicular compartments. Differential expression of both isoforms is also observed in other brain region: isoform 1 is very abundant in the gray matter of the frontal cortex, but is not associated with neuronal cell bodies. Not detected in the white matter. In contrast, isoform 2 is associated with neuronal bodies and axons in both the gray and the white matters of the frontal cortex.
Function
Mediates the Na(+)-independent transport of organic anions such as estrone-3-sulfate. Mediates transport of prostaglandins (PG) E1 and E2, thyroxine (T4), deltorphin II, BQ-123 and vasopressin, but not DPDPE (a derivative of enkephalin lacking an N-terminal tyrosine residue), estrone-3-sulfate, taurocholate, digoxin nor DHEAS.
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
Product Categories/Family for anti-SLCO3A1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
76,553 Da
NCBI Official Full Name
PGE1 transporter
NCBI Official Synonym Full Names
solute carrier organic anion transporter family, member 3A1
NCBI Official Symbol
SLCO3A1
NCBI Official Synonym Symbols
OATPD; OATP-D; OATP3A1; SLC21A11
NCBI Protein Information
solute carrier organic anion transporter family member 3A1; OATPRP3; OATP-RP3; PGE1 transporter; solute carrier family 21 member 11; organic anion-transporting polypeptide D; sodium-independent organic anion transporter D; organic anion transporter polype
UniProt Protein Name
Solute carrier organic anion transporter family member 3A1
Protein Family
UniProt Gene Name
SLCO3A1
UniProt Synonym Gene Names
OATP3A1; OATPD; SLC21A11; OATP3A1; OATP-RP3; OATPRP3; OATP-D
UniProt Entry Name
SO3A1_HUMAN
Uniprot Description
SLCO3A1: Mediates the Na(+)-independent transport of organic anions such as estrone-3-sulfate (PubMed:10873595). Mediates transport of prostaglandins (PG) E1 and E2, thyroxine (T4), deltorphin II, BQ-123 and vasopressin, but not DPDPE (a derivative of enkephalin lacking an N-terminal tyrosine residue), estrone-3- sulfate, taurocholate, digoxin nor DHEAS (PubMed:16971491). Belongs to the organo anion transporter (TC 2.A.60) family. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Transporter; Membrane protein, multi-pass; Transporter, SLC family; Membrane protein, integral
Chromosomal Location of Human Ortholog: 15q26
Cellular Component: plasma membrane; integral to membrane
Molecular Function: transporter activity
Biological Process: sodium-independent organic anion transport; transmembrane transport
Research Articles on SLCO3A1
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Product Notes
The SLCO3A1 slco3a1 (Catalog #AAA9630040) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SLCO3A1 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's SLCO3A1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA)(peptide). ELISA(peptide): 1:20000-1:40000. Researchers should empirically determine the suitability of the SLCO3A1 slco3a1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SLCO3A1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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