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Goat Slc8a3 Polyclonal Antibody | anti-Slc8a3 antibody

Goat anti-Slc8a3 (mouse) Antibody

Gene Names
Slc8a3; Ncx3; AW742262
Reactivity
Expected from sequence similarity: Mouse
Applications
ELISA
Purity
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Synonyms
Slc8a3; Polyclonal Antibody; Goat anti-Slc8a3 (mouse) Antibody; solute carrier family 8 (sodium/calcium exchanger); member 3; AW742262; MGC90626; Ncx3; Slc8a3 antibody; member 3 antibody; AW742262 antibody; MGC90626 antibody; Ncx3 antibody; Slc8a3 (mouse); anti-Slc8a3 antibody
Ordering
For Research Use Only!
Host
Goat
Reactivity
Expected from sequence similarity: Mouse
Clonality
Polyclonal
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Concentration
100ug specific antibody in 200ul (varies by lot)
Sequence
CLRAEAGDSGDVPS
Sequence Length
921
Applicable Applications for anti-Slc8a3 antibody
Peptide ELISA (EIA)
Application Notes
Peptide ELISA: Antibody detection limit dilution 1: 64000.
Western Blot: Preliminary experiments gave an approx 28kDa band in Mouse Brain lysates after 1ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 102kDa according to NP_001161392.1. The 28kDa band was successfully blocked by incubation with the immunizing peptide.
Immunogen
Peptide with sequence CLRAEAGDSGDVPS, from the N Terminus of the protein sequence according to NP_001161392.1; NP_536688.2.
Epitope
N Terminus
Note
This antibody is expected to recognize both reported isoforms (NP_001161392.1; NP_536688.2).
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
102,377 Da
NCBI Official Full Name
sodium/calcium exchanger 3 isoform 1
NCBI Official Synonym Full Names
solute carrier family 8 (sodium/calcium exchanger), member 3
NCBI Official Symbol
Slc8a3
NCBI Official Synonym Symbols
Ncx3; AW742262
NCBI Protein Information
sodium/calcium exchanger 3
UniProt Protein Name
Sodium/calcium exchanger 3
Protein Family
UniProt Gene Name
Slc8a3
UniProt Entry Name
NAC3_MOUSE

Uniprot Description

SLC8A3: Rapidly transports Ca(2+) during excitation-contraction coupling. Ca(2+) is extruded from the cell during relaxation so as to prevent overloading of intracellular stores. Belongs to the sodium/potassium/calcium exchanger family. SLC8 subfamily. 6 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, multi-pass; Transporter; Transporter, SLC family; Membrane protein, integral

Cellular Component: cell junction; cell projection; cell soma; cytoplasm; dendritic spine; endoplasmic reticulum; endoplasmic reticulum membrane; integral to membrane; integral to plasma membrane; intrinsic to plasma membrane; membrane; microtubule; mitochondrial outer membrane; mitochondrion; neuromuscular junction; perinuclear region of cytoplasm; plasma membrane; sarcolemma

Molecular Function: antiporter activity; calcium:cation antiporter activity; calcium:sodium antiporter activity; calmodulin binding; metal ion binding

Biological Process: calcium ion transport; cell communication; cellular calcium ion homeostasis; hemopoietic progenitor cell differentiation; ion transport; learning; memory; metal ion transport; mitochondrial calcium ion homeostasis; mitochondrial calcium ion transport; myelination; oligodendrocyte differentiation; regulation of skeletal muscle contraction; sodium ion transport; transmembrane transport; transport

Research Articles on Slc8a3

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Product Notes

The Slc8a3 slc8a3 (Catalog #AAA422982) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Goat anti-Slc8a3 (mouse) Antibody reacts with Expected from sequence similarity: Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Slc8a3 can be used in a range of immunoassay formats including, but not limited to, Peptide ELISA (EIA). Peptide ELISA: Antibody detection limit dilution 1: 64000. Western Blot: Preliminary experiments gave an approx 28kDa band in Mouse Brain lysates after 1ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 102kDa according to NP_001161392.1. The 28kDa band was successfully blocked by incubation with the immunizing peptide. Researchers should empirically determine the suitability of the Slc8a3 slc8a3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: CLRAEAGDSG DVPS. It is sometimes possible for the material contained within the vial of "Slc8a3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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