Western Blot (WB)
(Fig. Western Blot analysis of COLO cells using SLC4A8/10 Polyclonal Antibody diluted at 1:500.)
Rabbit SLC4A8/10 Polyclonal Antibody | anti-SLC4A8/10 antibody
SLC4A8/10 Polyclonal Antibody
Gene Names
SLC4A8; NBC3; NDCBE
Reactivity
Human, Mouse, Rat
Applications
Western Blot, Immunohistochemistry, ELISA
Purity
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
SLC4A8/10; Polyclonal Antibody; SLC4A8/10 Polyclonal Antibody; Rabbit Anti-SLC4A8/10 Polyclonal Antibody; SLC4A8; KIAA0739; NBC; NBC3; NDCBE1; Electroneutral sodium bicarbonate exchanger 1; Electroneutral Na(+)-driven Cl-HCO3 exchanger; Solute carrier family 4 member 8; k-NBC3; SLC4A10; NCBE; Sodium-driven chloride bicarbonate exchanger; Solute; anti-SLC4A8/10 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
SLC4A8/10 Polyclonal Antibody detects endogenous levels of SLC4A8/10 protein.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
Liquid; PBS Containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Concentration
1 mg/ml (varies by lot)
Sequence Length
691
Applicable Applications for anti-SLC4A8/10 antibody
Western Blot (WB), Immunohistochemistry (IHC) Paraffin, ELISA (EIA)
Application Notes
WB: 1:500-1:2000
IHC-P: 1:100-1:300
ELISA: 1:40000
IHC-P: 1:100-1:300
ELISA: 1:40000
Immunogen
Synthesized peptide derived from the internal region of human SLC4A8/10 at AA range: 380-460
Preparation and Storage
Stable for one year at -20 degree C from date of shipment.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Western Blot (WB)
(Fig. Western Blot analysis of COLO cells using SLC4A8/10 Polyclonal Antibody diluted at 1:500.)
Western Blot (WB)
(Fig. Western Blot analysis of COLO cells using SLC4A8/10 Polyclonal Antibody diluted at 1:500.)
Related Product Information for anti-SLC4A8/10 antibody
SLC4A10 (solute carrier family 4 member 10) belongs to a small family of sodium-coupled bicarbonate transporters (NCBTs) that regulate the intracellular pH of neurons, the secretion of bicarbonate ions across the choroid plexus, and the pH of the brain extracellular fluid. The protein encoded by SLC4A10 was initially identified as a sodium-driven chloride bicarbonate exchanger (NCBE) though there is now evidence that its sodium/bicarbonate cotransport activity is independent of any chloride ion countertransport under physiological conditions. SLC4A10 is now classified as a member A10 of the SLC4 family of transmembrane solute carriers. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
electroneutral sodium bicarbonate exchanger 1 isoform d
NCBI Official Synonym Full Names
solute carrier family 4 member 8
NCBI Official Symbol
SLC4A8
NCBI Official Synonym Symbols
NBC3; NDCBE
NCBI Protein Information
electroneutral sodium bicarbonate exchanger 1
UniProt Protein Name
Electroneutral sodium bicarbonate exchanger 1
UniProt Gene Name
SLC4A8
UniProt Entry Name
S4A8_HUMAN
NCBI Description
The protein encoded by this gene is a membrane protein that functions to transport sodium and bicarbonate ions across the cell membrane. The encoded protein is important for pH regulation in neurons. The activity of this protein can be inhibited by 4,4'-Di-isothiocyanatostilbene-2,2'-disulfonic acid (DIDS). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]
Research Articles on SLC4A8/10
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Product Notes
The SLC4A8/10 slc4a8 (Catalog #AAA9706514) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SLC4A8/10 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's SLC4A8/10 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC) Paraffin, ELISA (EIA). WB: 1:500-1:2000 IHC-P: 1:100-1:300 ELISA: 1:40000. Researchers should empirically determine the suitability of the SLC4A8/10 slc4a8 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SLC4A8/10, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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