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Western Blot (WB) (Western blot analysis of extracts of various cell lines, using SLC39A8 antibody at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit.Exposure time: 90s.)

Rabbit anti-Human, Mouse SLC39A8 Polyclonal Antibody | anti-SLC39A8 antibody

SLC39A8 Polyclonal Antibody

Gene Names
SLC39A8; ZIP8; CDG2N; PP3105; BIGM103; LZT-Hs6
Reactivity
Human, Mouse
Applications
Western Blot
Purity
Affinity Purification
Synonyms
SLC39A8; Polyclonal Antibody; SLC39A8 Polyclonal Antibody; BIGM103; CDG2N; LZT-Hs6; PP3105; ZIP8; anti-SLC39A8 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity Purification
Sequence Length
460
Applicable Applications for anti-SLC39A8 antibody
Western Blot (WB)
Application Notes
WB: 1:500 - 1:2000
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 180-300 of human SLC39A8 (NP_071437.3)
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Calculated MW
43kDa/48kDa/49kDa
Observed MW
50kDa
Preparation and Storage
Store at -20°C. Avoid freeze/thaw cycles.

Western Blot (WB)

(Western blot analysis of extracts of various cell lines, using SLC39A8 antibody at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit.Exposure time: 90s.)

Western Blot (WB) (Western blot analysis of extracts of various cell lines, using SLC39A8 antibody at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit.Exposure time: 90s.)
Related Product Information for anti-SLC39A8 antibody
This gene encodes a member of the SLC39 family of solute-carrier genes, which show structural characteristics of zinc transporters. The encoded protein is glycosylated and found in the plasma membrane and mitochondria, and functions in the cellular import of zinc at the onset of inflammation. It is also thought to be the primary transporter of the toxic cation cadmium, which is found in cigarette smoke. Multiple transcript variants encoding different isoforms have been found for this gene. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.
Product Categories/Family for anti-SLC39A8 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
NCBI Official Full Name
Zinc transporter ZIP8
NCBI Official Synonym Full Names
solute carrier family 39 member 8
NCBI Official Symbol
SLC39A8
NCBI Official Synonym Symbols
ZIP8; CDG2N; PP3105; BIGM103; LZT-Hs6
NCBI Protein Information
zinc transporter ZIP8
UniProt Protein Name
Zinc transporter ZIP8
Protein Family
UniProt Gene Name
SLC39A8
UniProt Synonym Gene Names
BIGM103; ZIP8; LZT-Hs6; ZIP-8

NCBI Description

This gene encodes a member of the SLC39 family of solute-carrier genes, which show structural characteristics of zinc transporters. The encoded protein is glycosylated and found in the plasma membrane and mitochondria, and functions in the cellular import of zinc at the onset of inflammation. It is also thought to be the primary transporter of the toxic cation cadmium, which is found in cigarette smoke. Multiple transcript variants encoding different isoforms have been found for this gene. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Oct 2008]

Uniprot Description

SLC39A8: Acts as a zinc-influx transporter. Belongs to the ZIP transporter (TC 2.A.5) family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, SLC family

Chromosomal Location of Human Ortholog: 4q24

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: zinc ion transmembrane transporter activity

Biological Process: cellular zinc ion homeostasis; zinc ion transport

Disease: Congenital Disorder Of Glycosylation, Type Iin

Research Articles on SLC39A8

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Product Notes

The SLC39A8 slc39a8 (Catalog #AAA9130903) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SLC39A8 Polyclonal Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's SLC39A8 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500 - 1:2000. Researchers should empirically determine the suitability of the SLC39A8 slc39a8 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SLC39A8, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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