Goat SLC25A38 Polyclonal Antibody | anti-SLC25A38 antibody
Goat anti-SLC25A38 Antibody
Western Blot: Preliminary experiments in lysates of cell lines Jurkat and K562 gave no specific signal but low background (at antibody concentration up to 2ug/ml).
NCBI and Uniprot Product Information
NCBI Description
This gene is a member of the mitochondrial carrier family. The encoded protein is required during erythropoiesis and is important for the biosynthesis of heme. Mutations in this gene are the cause of autosomal congenital sideroblastic anemia.[provided by RefSeq, Mar 2010]
Uniprot Description
SLC25A38: Mitochondrial carrier required during erythropoiesis. Probably involved in the biosynthesis of heme, possibly by facilitating 5-aminolevulinate (ALA) production. May act by importing glycine into mitochondria or by exchanging glycine for ALA across the mitochondrial inner membrane. Defects in SLC25A38 are a cause of anemia sideroblastic pyridoxine-refractory autosomal recessive (PRARSA). A form of sideroblastic anemia not responsive to pyridoxine. Sideroblastic anemia is characterized by anemia of varying severity, hypochromic peripheral erythrocytes, systemic iron overload secondary to chronic ineffective erythropoiesis, and the presence of bone marrow ringed sideroblasts. Sideroblasts are characterized by iron-loaded mitochondria clustered around the nucleus. Belongs to the mitochondrial carrier family. SLC25A38 subfamily.
Protein type: Membrane protein, multi-pass; Membrane protein, integral; Transporter; Transporter, SLC family; Mitochondrial
Chromosomal Location of Human Ortholog: 3p22.1
Cellular Component: integral to membrane; mitochondrial inner membrane
Molecular Function: structural constituent of ribosome; transporter activity
Biological Process: erythrocyte differentiation; heme biosynthetic process; translation; transport
Disease: Anemia, Sideroblastic, Pyridoxine-refractory, Autosomal Recessive
Research Articles on SLC25A38
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Product Notes
The SLC25A38 slc25a38 (Catalog #AAA423015) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Goat anti-SLC25A38 Antibody reacts with Expected from sequence similarity: Human, Mouse, Rat, Dog, Cow, Sheep and may cross-react with other species as described in the data sheet. AAA Biotech's SLC25A38 can be used in a range of immunoassay formats including, but not limited to, Peptide ELISA (EIA). Peptide ELISA: Antibody detection limit dilution 1: 32000. Western Blot: Preliminary experiments in lysates of cell lines Jurkat and K562 gave no specific signal but low background (at antibody concentration up to 2ug/ml). Researchers should empirically determine the suitability of the SLC25A38 slc25a38 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: PITVIKTRYE SGK. It is sometimes possible for the material contained within the vial of "SLC25A38, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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