Rabbit anti-Human SLC24A3 Polyclonal Antibody | anti-SLC24A3 antibody
SLC24A3, NT (SLC24A3, NCKX3, Sodium/potassium/calcium exchanger 3, Na(+)/K(+)/Ca(2+)-exchange protein 3, Solute carrier family 24 member 3) (MaxLight 490)
Gene Names
SLC24A3; NCKX3
Reactivity
Human
Applications
Western Blot
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
SLC24A3; Polyclonal Antibody; NT (SLC24A3; NCKX3; Sodium/potassium/calcium exchanger 3; Na(+)/K(+)/Ca(2+)-exchange protein 3; Solute carrier family 24 member 3) (MaxLight 490); Solute carrier family 24 member 3; anti-SLC24A3 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight490.
Applicable Applications for anti-SLC24A3 antibody
Western Blot (WB), FLISA
Application Notes
WB: 1:100-500
FLISA: 1:1,000
Applications are based on unconjugated antibody.
FLISA: 1:1,000
Applications are based on unconjugated antibody.
Immunogen
SLC24A3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 78-108 amino acids from the N-terminal region of human SLC24A3.
Conjugate
MaxLight490
Note
Preservative Free
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight490 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Related Product Information for anti-SLC24A3 antibody
Plasma membrane sodium/calcium exchangers are an important component of intracellular calcium homeostasis and electrical conduction. Potassium-dependent sodium/calcium exchangers such as SLC24A3 are believed to transport 1 intracellular calcium and 1 potassium ion in exchange for 4 extracellular sodium ions (Kraev et al., 2001 [PubMed 11294880]).
Product Categories/Family for anti-SLC24A3 antibody
References
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010): Cheng, Y.C., et al. Circ Cardiovasc Genet 2(4):329-337(2009). Deloukas, P., et al. Nature 414(6866):865-871(2001). Kraev, A., et al. J. Biol. Chem. 276(25):23161-23172(2001).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
71,992 Da
NCBI Official Full Name
sodium/potassium/calcium exchanger 3
NCBI Official Synonym Full Names
solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
NCBI Official Symbol
SLC24A3
NCBI Official Synonym Symbols
NCKX3
NCBI Protein Information
sodium/potassium/calcium exchanger 3; sodium calcium exchanger; solute carrier family 24 member 3; Na(+)/K(+)/Ca(2+)-exchange protein 3
UniProt Protein Name
Sodium/potassium/calcium exchanger 3
Protein Family
UniProt Gene Name
SLC24A3
UniProt Synonym Gene Names
NCKX3
UniProt Entry Name
NCKX3_HUMAN
NCBI Description
Plasma membrane sodium/calcium exchangers are an important component of intracellular calcium homeostasis and electrical conduction. Potassium-dependent sodium/calcium exchangers such as SLC24A3 are believed to transport 1 intracellular calcium and 1 potassium ion in exchange for 4 extracellular sodium ions (Kraev et al., 2001 [PubMed 11294880]).[supplied by OMIM, Mar 2008]
Uniprot Description
SLC24A3: Transports 1 Ca(2+) and 1 K(+) in exchange for 4 Na(+). Belongs to the sodium/potassium/calcium exchanger family. SLC24A subfamily.
Protein type: Membrane protein, integral; Transporter, SLC family; Membrane protein, multi-pass; Transporter
Chromosomal Location of Human Ortholog: 20p13
Cellular Component: integral to membrane; plasma membrane
Molecular Function: calcium, potassium:sodium antiporter activity; symporter activity
Biological Process: calcium ion transport; ion transport; transmembrane transport; potassium ion transport
Research Articles on SLC24A3
Similar Products
Product Notes
The SLC24A3 slc24a3 (Catalog #AAA6348204) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SLC24A3, NT (SLC24A3, NCKX3, Sodium/potassium/calcium exchanger 3, Na(+)/K(+)/Ca(2+)-exchange protein 3, Solute carrier family 24 member 3) (MaxLight 490) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SLC24A3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), FLISA. WB: 1:100-500 FLISA: 1:1,000 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the SLC24A3 slc24a3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SLC24A3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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