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Immunohistochemistry (IHC) (Anti-SLC1A4 antibody IHC of human brain-cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Rabbit SLC1A4 / ASCT1 Polyclonal Antibody | anti-SLC1A4 antibody

Rabbit Polyclonal to Human SLC1A4 / ASCT1

Gene Names
SLC1A4; SATT; ASCT1
Reactivity
Gibbon, Dog, Gorilla, Human
Predicted Reactivity: Monkey, Mouse, Hamster, Horse, Rabbit (at least 90% immunogen sequence identity)
Applications
Immunohistochemistry
Purity
Immunoaffinity Purified
Synonyms
SLC1A4 / ASCT1; Polyclonal Antibody; Rabbit Polyclonal to Human SLC1A4 / ASCT1; Anti-SLC1A4 / ASCT1 Antibody (C-Terminus) IHC-plus; SLC1A4; ASCT1; SATT; ASCT-1; Human SLC1A4; anti-SLC1A4 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Gibbon, Dog, Gorilla, Human
Predicted Reactivity: Monkey, Mouse, Hamster, Horse, Rabbit (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Specificity
Human SLC1A4. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Purity/Purification
Immunoaffinity Purified
Form/Format
PBS, 0.1% sodium azide.
Concentration
1 mg/ml (varies by lot)
Sequence Length
532
Applicable Applications for anti-SLC1A4 antibody
Immunohistochemistry (IHC - Paraffin)
Application Notes
IHC-P (10 - 12.5 ug/ml)
Target Species
Human
Immunogen Description
Synthetic 17 amino acid peptide from C-terminus of human SLC1A4. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Dog, Panda, Opossum (100%); Marmoset, Mouse, Hamster, Rabbit, Horse, Platypus (94%).
Immunogen Type
Synthetic peptide
Immunogen
SLC1A4 / ASCT1 antibody was raised against synthetic 17 amino acid peptide from C-terminus of human SLC1A4. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Dog, Panda, Opossum (100%); Marmoset, Mouse, Hamster, Rabbit, Horse, Platypus (94%); Rat, Elephant (88%); Bovine (82%).
Antigen Modification
C-Terminus
Preparation and Storage
Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles.

Immunohistochemistry (IHC)

(Anti-SLC1A4 antibody IHC of human brain-cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Immunohistochemistry (IHC) (Anti-SLC1A4 antibody IHC of human brain-cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Immunohistochemistry (IHC)

(Anti-SLC1A4 antibody IHC of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Immunohistochemistry (IHC) (Anti-SLC1A4 antibody IHC of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Related Product Information for anti-SLC1A4 antibody
ASCT1 functions primarily as a neutral amino acid exchanger. ASCT 1-mediated transport requires the presence of sodium ions but ASCT1 mediates only homo- and hetero exchange of amino acids and is insensitive to K+. The properties of ASCT1 suggest that it may function to equilibrate different pools of neutral amino acids and provide a mechanism to link amino acid concentration gradients. ASCT1 expression has been found at varying levels in every tissue examined.
Product Categories/Family for anti-SLC1A4 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
24,620 Da
NCBI Official Full Name
neutral amino acid transporter A isoform 1
NCBI Official Synonym Full Names
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
NCBI Official Symbol
SLC1A4
NCBI Official Synonym Symbols
SATT; ASCT1
NCBI Protein Information
neutral amino acid transporter A; ASCT-1; solute carrier family 1 member 4; glutamate/neutral amino acid transporter; alanine/serine/cysteine/threonine transporter 1
UniProt Protein Name
Neutral amino acid transporter A
UniProt Gene Name
SLC1A4
UniProt Synonym Gene Names
ASCT1; SATT; ASCT-1
UniProt Entry Name
SATT_HUMAN

Uniprot Description

SLC1A4: Transporter for alanine, serine, cysteine, and threonine. Exhibits sodium dependence. Expressed mostly in brain, muscle, and pancreas but detected in all tissues examined. Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family. SLC1A4 subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Transporter; Transporter, SLC family; Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 2p15-p13

Cellular Component: centrosome; cell surface; cell soma; membrane; integral to plasma membrane; dendrite; integral to membrane; melanosome; plasma membrane; intermediate filament; microtubule organizing center

Molecular Function: L-serine transmembrane transporter activity; chloride channel activity; L-threonine transmembrane transporter activity; L-proline transmembrane transporter activity; L-alanine transmembrane transporter activity; L-glutamine transmembrane transporter activity; sodium:dicarboxylate symporter activity; L-cystine transmembrane transporter activity

Biological Process: synaptic transmission, glutamatergic; threonine transport; L-cystine transport; chloride transport; L-alanine transport; L-serine transport; amino acid transport; dicarboxylic acid transport; ion transport; cognition; glutamine transport; proline transport; transmembrane transport

Research Articles on SLC1A4

Similar Products

Product Notes

The SLC1A4 slc1a4 (Catalog #AAA246958) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal to Human SLC1A4 / ASCT1 reacts with Gibbon, Dog, Gorilla, Human Predicted Reactivity: Monkey, Mouse, Hamster, Horse, Rabbit (at least 90% immunogen sequence identity) and may cross-react with other species as described in the data sheet. AAA Biotech's SLC1A4 / ASCT1 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin). IHC-P (10 - 12.5 ug/ml). Researchers should empirically determine the suitability of the SLC1A4 slc1a4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SLC1A4 / ASCT1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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