Western Blot (WB)
(Anti-SLC1A4 antibody, MBS176881, Western blottingLane 1: U87 Cell LysateLane 2: Rat Brain Tissue LysateLane 3: Mouse Brain Tissue Lysate )
Rabbit SLC1A4 Polyclonal Antibody | anti-SLC1A4 antibody
Anti-SLC1A4 antibody
Western Blot (WB)
(Anti-SLC1A4 antibody, MBS176881, Western blottingLane 1: U87 Cell LysateLane 2: Rat Brain Tissue LysateLane 3: Mouse Brain Tissue Lysate )
Western Blot (WB)
(Anti-SLC1A4 antibody, MBS176881, Western blottingLane 1: U87 Cell LysateLane 2: Rat Brain Tissue LysateLane 3: Mouse Brain Tissue Lysate )
Immunohistochemistry (IHC)
(Anti-SLC1A4 antibody, MBS176881, IHC(P)IHC(P): Human Intestinal Cancer Tissue )
Immunohistochemistry (IHC)
(Anti-SLC1A4 antibody, MBS176881, IHC(P)IHC(P): Human Intestinal Cancer Tissue )
Background: Neutral amino acid transporter A, also called SLC1A4 or ASCT1, is a protein that in humans is encodes by the SLC1A4 gene. The SLC1A4 gene is mapped to chromosome 2p14 based on an alignment of the SLC1A4 sequence with the genomic sequence(GRCh37). ASCT1 does not transport glutamate or aspartate but alanine, serine, cysteine, and threonine instead. It is found that the ASCT1 transporter functions primarily as an amino acid exchanger. Transport is associated with a chloride channel activity that is thermodynamically uncoupled from animo acid transport. This gene also exhibits sodium dependence.
NCBI and Uniprot Product Information
Uniprot Description
SLC1A4: Transporter for alanine, serine, cysteine, and threonine. Exhibits sodium dependence. Expressed mostly in brain, muscle, and pancreas but detected in all tissues examined. Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family. SLC1A4 subfamily. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Transporter; Membrane protein, multi-pass; Membrane protein, integral; Transporter, SLC family
Chromosomal Location of Human Ortholog: 2p15-p13
Cellular Component: centrosome; cell surface; membrane; cell soma; integral to plasma membrane; dendrite; integral to membrane; melanosome; plasma membrane; microtubule organizing center; intermediate filament
Molecular Function: L-serine transmembrane transporter activity; chloride channel activity; L-threonine transmembrane transporter activity; L-proline transmembrane transporter activity; L-alanine transmembrane transporter activity; L-cystine transmembrane transporter activity; sodium:dicarboxylate symporter activity; L-glutamine transmembrane transporter activity
Biological Process: synaptic transmission, glutamatergic; threonine transport; L-cystine transport; chloride transport; L-serine transport; L-alanine transport; dicarboxylic acid transport; amino acid transport; ion transport; proline transport; cognition; glutamine transport; transmembrane transport
Research Articles on SLC1A4
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Product Notes
The SLC1A4 slc1a4 (Catalog #AAA176881) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-SLC1A4 antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's SLC1A4 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC) Paraffin. Researchers should empirically determine the suitability of the SLC1A4 slc1a4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SLC1A4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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