Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human brain tissue using SLC17A7 Polyclonal Antibody at dilution of 1:200(×200))
Rabbit SLC17A7 Polyclonal Antibody | anti-SLC17A7 antibody
SLC17A7 Polyclonal Antibody
ELISA: 1:5000-1:240000
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human brain tissue using SLC17A7 Polyclonal Antibody at dilution of 1:200(×200))
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human brain tissue using SLC17A7 Polyclonal Antibody at dilution of 1:200(×200))
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a vesicle-bound, sodium-dependent phosphate transporter that is specifically expressed in the neuron-rich regions of the brain. It is preferentially associated with the membranes of synaptic vesicles and functions in glutamate transport. The protein shares 82% identity with the differentiation-associated Na-dependent inorganic phosphate cotransporter and they appear to form a distinct class within the Na+/Pi cotransporter family. [provided by RefSeq, Jul 2008]
Uniprot Description
SLC17A7: Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. May also mediate the transport of inorganic phosphate. Belongs to the major facilitator superfamily. Sodium/anion cotransporter family. VGLUT subfamily.
Protein type: Transporter, SLC family; Membrane protein, multi-pass; Vesicle; Membrane protein, integral; Transporter
Chromosomal Location of Human Ortholog: 19q13
Cellular Component: synaptic vesicle membrane; integral to membrane; presynaptic active zone; plasma membrane; excitatory synapse; cell junction
Molecular Function: sodium:inorganic phosphate symporter activity; sodium-dependent phosphate transmembrane transporter activity; inorganic phosphate transmembrane transporter activity; L-glutamate transmembrane transporter activity
Biological Process: synaptic transmission; synaptic transmission, glutamatergic; L-glutamate import; glutamate secretion; phosphate transport; long-term memory; neurotransmitter secretion; ion transport; regulation of excitatory postsynaptic membrane potential; sequestering of neurotransmitter; transmembrane transport
Research Articles on SLC17A7
Similar Products
Product Notes
The SLC17A7 slc17a7 (Catalog #AAA2563101) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SLC17A7 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's SLC17A7 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), ELISA (EIA). IHC: 1:200-1:500 ELISA: 1:5000-1:240000. Researchers should empirically determine the suitability of the SLC17A7 slc17a7 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SLC17A7, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
