Western Blot (WB)
(Western Blot (WB) analysis of SLC16A5 (A193) polyclonal antibody at 1:500 dillutionLane1:HEK293T whole cell lysate (40ug) Lane2:NIH-3T3 whole cell lysate (40ug) Lane3:PC12 whole cell lysate (40ug))
Rabbit SLC16A5 Polyclonal Antibody | anti-SLC16A5 antibody
SLC16A5 (A193) Polyclonal Antibody
Reactivity
Human, Mouse, Rat
Applications
Western Blot
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Synonyms
SLC16A5; Polyclonal Antibody; SLC16A5 (A193) Polyclonal Antibody; Monocarboxylate transporter 6; MCT 6; Monocarboxylate transporter 5; MCT 5; Solute carrier family 16 member 5; MCT5; MCT6; anti-SLC16A5 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
SLC16A5 (A193) polyclonal antibody detects endogenous levels of SLC16A5 protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Form/Format
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Sequence Length
505
Applicable Applications for anti-SLC16A5 antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:1000
Immunogen
Synthetic peptide, corresponding to amino acids 161-210 of Human SLC16A5.
Preparation and Storage
Store at 4 degree C short term.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Western Blot (WB)
(Western Blot (WB) analysis of SLC16A5 (A193) polyclonal antibody at 1:500 dillutionLane1:HEK293T whole cell lysate (40ug) Lane2:NIH-3T3 whole cell lysate (40ug) Lane3:PC12 whole cell lysate (40ug))
Western Blot (WB)
(Western Blot (WB) analysis of SLC16A5 (A193) polyclonal antibody at 1:500 dillutionLane1:HEK293T whole cell lysate (40ug) Lane2:NIH-3T3 whole cell lysate (40ug) Lane3:PC12 whole cell lysate (40ug))
Related Product Information for anti-SLC16A5 antibody
Monocarboxylates, such as lactate and pyruvate, play an integral role in cellular metabolism. Lactic acid is produced in large quantities as a result of glycolysis, which provides the majority of ATP to cells under normal physiological conditions. However, accumulation of lactic acid leads to a decrease in intracellular pH and cessation of glycolysis. In order for glycolysis to continue at a high rate, lactic acid must be transported out of the cell. This transport process is carried out by a family of monocarboxylate transporters (MCTs), which function as proton symports and are stereoselective for L-lactate. The MCT family consists of at least eight members, MCT1-8, which contain between 10-12 transmembrane-helical (TM) domains, with the amino and carboxy termini located in the cytoplasm. MCT6 is highly expressed in the kidneys and is thought to have a specificity for bumetanide, a loop diuretic involved in the treatment of edema. The high substrate specificity of MCT6 suggests a possible role in therapeutic drug transport and trafficking across the plasma membrane.
NCBI and Uniprot Product Information
NCBI GI #
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
~ 55kDa
NCBI Official Full Name
monocarboxylate transporter 6
UniProt Protein Name
Monocarboxylate transporter 6
Protein Family
UniProt Gene Name
SLC16A5
UniProt Synonym Gene Names
MCT5; MCT6
UniProt Entry Name
MOT6_HUMAN
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Product Notes
The SLC16A5 slc16a5 (Catalog #AAA3000215) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SLC16A5 (A193) Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's SLC16A5 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:1000. Researchers should empirically determine the suitability of the SLC16A5 slc16a5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SLC16A5, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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