Western Blot (WB)
(SLAMF7 Antibody (Center) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the SLAMF7 antibody detected the SLAMF7 protein (arrow).)
Rabbit anti-Human SLAMF7 Polyclonal Antibody | anti-SLAMF7 antibody
SLAMF7 Antibody (Center)
Gene Names
SLAMF7; 19A; CS1; CD319; CRACC
Reactivity
Human
Applications
Western Blot, ELISA
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
SLAMF7; Polyclonal Antibody; SLAMF7 Antibody (Center); SLAM family member 7; CD2 subset 1; CD2-like receptor-activating cytotoxic cells; CRACC; Membrane protein FOAP-12; Novel Ly9; Protein 19A; CD319; CS1; anti-SLAMF7 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This SLAMF7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 58-85 amino acids from the Central region of human SLAMF7.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
58-85
Sequence Length
188
Applicable Applications for anti-SLAMF7 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB~~1:1000
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Western Blot (WB)
(SLAMF7 Antibody (Center) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the SLAMF7 antibody detected the SLAMF7 protein (arrow).)
Western Blot (WB)
(SLAMF7 Antibody (Center) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the SLAMF7 antibody detected the SLAMF7 protein (arrow).)
Related Product Information for anti-SLAMF7 antibody
SLAMF7 contains one Ig-like C2-type (immunoglobulin-like) domain. Isoform 1 mediates NK cell activation through a SAP-independent extracellular signal-regulated ERK-mediated pathway. It may play a role in lymphocyte adhesion. Isoform 3 does not mediate any activation. SAP can bind the cytoplasmic tail of isoform 1 when phosphorylated in the presence of Fyn (in vitro). SLAMF7 is expressed in spleen, lymph node, peripheral blood leukocytes, bone marrow, small intestine, stomach, appendix, lung and trachea. Expression was detected in NK cells, activated B-cells, NK-cell line but not in promyelocytic, B-, or T-cell lines. The isoform 3 is expressed at much lower level than isoform 1. There are three named isoforms.
Product Categories/Family for anti-SLAMF7 antibody
References
Tovar, V., et al. Immunogenetics 54(6):394-402(2002)
Murphy, J.J., et al. Biochem. J. 361 (PT 3), 431-436 (2002)
Bouchon, A., et al. J. Immunol. 167(10):5517-5521(2001)
Boles, K.S., et al. Immunogenetics 52 (3-4), 302-307 (2001)
Murphy, J.J., et al. Biochem. J. 361 (PT 3), 431-436 (2002)
Bouchon, A., et al. J. Immunol. 167(10):5517-5521(2001)
Boles, K.S., et al. Immunogenetics 52 (3-4), 302-307 (2001)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
37421
NCBI Official Full Name
SLAM family member 7 isoform a
NCBI Official Synonym Full Names
SLAM family member 7
NCBI Official Symbol
SLAMF7
NCBI Official Synonym Symbols
19A; CS1; CD319; CRACC
NCBI Protein Information
SLAM family member 7
UniProt Protein Name
SLAM family member 7
Protein Family
UniProt Gene Name
SLAMF7
UniProt Synonym Gene Names
CS1; CRACC
UniProt Entry Name
SLAF7_HUMAN
Uniprot Description
SLAMF7: Isoform 1 mediates NK cell activation through a SH2D1A- independent extracellular signal-regulated ERK-mediated pathway. May play a role in lymphocyte adhesion. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral; Immunoglobulin superfamily
Chromosomal Location of Human Ortholog: 1q23.1-q24.1
Cellular Component: integral to membrane
Molecular Function: receptor activity
Biological Process: natural killer cell mediated cytotoxicity; natural killer cell activation; cell adhesion
Research Articles on SLAMF7
Similar Products
Product Notes
The SLAMF7 slamf7 (Catalog #AAA9209382) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 58-85. The SLAMF7 Antibody (Center) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SLAMF7 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the SLAMF7 slamf7 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SLAMF7, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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