Western Blot (WB)
(Western Blot analysis of various cells using CD172b Polyclonal Antibody)
Rabbit anti-Human SIRPB1 Polyclonal Antibody | anti-SIRPB1 antibody
SIRPB1 polyclonal antibody
ELISA: 1/5000
Western Blot (WB)
(Western Blot analysis of various cells using CD172b Polyclonal Antibody)
Western Blot (WB)
(Western Blot analysis of various cells using CD172b Polyclonal Antibody)
Western Blot (WB)
(Western blot analysis of lysates from HeLa, COLO, and HUVEC cells, using SIRPB1 Antibody. The lane on the right is blocked with the synthesized peptide.)
Western Blot (WB)
(Western blot analysis of lysates from HeLa, COLO, and HUVEC cells, using SIRPB1 Antibody. The lane on the right is blocked with the synthesized peptide.)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein was found to interact with TYROBP/DAP12, a protein bearing immunoreceptor tyrosine-based activation motifs. This protein was also reported to participate in the recruitment of tyrosine kinase SYK. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2009]
Uniprot Description
SIRPB1: Immunoglobulin-like cell surface receptor involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. Participates also in the recruitment of tyrosine kinase SYK. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral
Chromosomal Location of Human Ortholog: 20p13
Cellular Component: integral to plasma membrane; integral to membrane; plasma membrane
Molecular Function: protein binding
Biological Process: cell surface receptor linked signal transduction; innate immune response; signal transduction
Research Articles on SIRPB1
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Product Notes
The SIRPB1 sirpb1 (Catalog #AAA3001941) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SIRPB1 polyclonal antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SIRPB1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1/500-1/2000 ELISA: 1/5000. Researchers should empirically determine the suitability of the SIRPB1 sirpb1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SIRPB1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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