Rabbit anti-Human Siglec 11 Polyclonal Antibody | anti-SIGLEC11 antibody

Siglec 11, CT (Sialic Acid-binding Ig-like Lectin 11, Sialic Acid-binding Lectin 11, Siglec 11, UNQ9222/PRO28718) (MaxLight 550)

Cat. Num. AAA6499486

• Reactivity: Human
• Applications: Immunohistochemistry, Western Blot
• Purity: Purified by Protein G Affinity Chromatography.
• Synonyms: Siglec 11; Polyclonal Antibody; CT (Sialic Acid-binding Ig-like Lectin 11; Sialic Acid-binding Lectin 11; UNQ9222/PRO28718) (MaxLight 550); anti-SIGLEC11 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human SIGLEC11.
• Purity/Purification: Purified by Protein G Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight550.
• Sequence Length: 686

• Applicable Applications for anti-SIGLEC11 antibody: Immunohistochemistry (IHC), FLISA, Western Blot (WB)
• Application Notes: IHC: 1:50-1:100; FLISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 631-662 in the C-terminal region of human Siglec 11, UniProt Accession #AAK72907; Q96RL6.
• Conjugate: MaxLight550
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight550 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(Western Blot analysis in MCF-7 cell line lysates (35ug/lane) using MBS626763. This demonstrates that MBS626763 detected the SIGLEC11 protein (arrow).)

Immunohistochemistry (IHC)

(Immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue using MBS626763 followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of MBS626763 for immunohistochemistry.)

Product Categories/Family for anti-SIGLEC11 antibody

Antibodies; Lectins

References

1. Clark, H.F., et al., Genome Res. 13(10):2265-2270 (2003). 2. Angata, T., et al., J. Biol. Chem. 277(27):24466-24474 (2002).

NCBI and Uniprot Product Information

• NCBI GI #: 14718451
• NCBI GeneID: 114132
• Molecular Weight: 74.544
• NCBI Official Full Name: sialic acid-binding lectin 11
• NCBI Official Synonym Full Names: sialic acid binding Ig like lectin 11
• NCBI Official Symbol: SIGLEC11
• NCBI Protein Information: sialic acid-binding Ig-like lectin 11
• Protein Family: Sialic acid-binding Ig-like lectin

NCBI Description

This gene encodes a member of the sialic acid-binding immunoglobulin-like lectin family. These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain. This family member mediates anti-inflammatory and immunosuppressive signaling. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]