Western Blot (WB)
(SIA8C Antibody (C-term) western blot analysis in HL-60 cell line lysates (15ug/lane).This demonstrates the SIA8C antibody detected the SIA8C protein (arrow).)
Rabbit anti-Human SIA8C Polyclonal Antibody | anti-SIA8C antibody
SIA8C, CT (ST8SIA3, SIAT8C, Sia-alpha-2,3-Gal-beta-1,4-GlcNAc-R:alpha 2,8-sialyltransferase, Alpha-2,8-sialyltransferase 8C, Alpha-2,8-sialyltransferase III, ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3, Sialyltransferase 8C, Sialytransfer
ELISA: 1:1,000
Applications are based on unconjugated antibody.
Western Blot (WB)
(SIA8C Antibody (C-term) western blot analysis in HL-60 cell line lysates (15ug/lane).This demonstrates the SIA8C antibody detected the SIA8C protein (arrow).)
Western Blot (WB)
(SIA8C Antibody (C-term) western blot analysis in HL-60 cell line lysates (15ug/lane).This demonstrates the SIA8C antibody detected the SIA8C protein (arrow).)
Flow Cytometry (FC/FACS)
(SIA8C Antibody (C-term) flow cytometric analysis of HL-60 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
Flow Cytometry (FC/FACS)
(SIA8C Antibody (C-term) flow cytometric analysis of HL-60 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
NCBI and Uniprot Product Information
NCBI Description
ST8SIA3 belongs to a family of sialyltransferases that form sialyl-alpha-2,8-sialyl-R linkages at the nonreducing termini of glycoconjugates (Lee et al., 1998 [PubMed 9826427]).[supplied by OMIM, Mar 2008]
Uniprot Description
ST8SIA3: May transfer sialic acid through alpha-2,8-linkages to alpha-2,3-linked and alpha-2,8-linked sialic acid of N-linked oligosaccharides of glycoproteins and glycolipids. It can form polysialic acid in vitro directly on alpha-2,3-, alpha-2,6-, or alpha-2,8-linked sialic acid. Belongs to the glycosyltransferase 29 family.
Protein type: Membrane protein, integral; Transferase; EC 2.4.99.-; Glycan Metabolism - glycosphingolipid biosynthesis - ganglio series
Chromosomal Location of Human Ortholog: 18q21.31
Cellular Component: Golgi membrane; integral to Golgi membrane
Molecular Function: alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity; sialic acid binding
Biological Process: glycosphingolipid biosynthetic process; cellular protein metabolic process; dolichol-linked oligosaccharide biosynthetic process; glycoprotein metabolic process; protein amino acid glycosylation; protein amino acid N-linked glycosylation via asparagine; N-glycan processing; post-translational protein modification; oligosaccharide metabolic process; ganglioside biosynthetic process
Research Articles on SIA8C
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Product Notes
The SIA8C st8sia3 (Catalog #AAA6347509) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SIA8C, CT (ST8SIA3, SIAT8C, Sia-alpha-2,3-Gal-beta-1,4-GlcNAc-R:alpha 2,8-sialyltransferase, Alpha-2,8-sialyltransferase 8C, Alpha-2,8-sialyltransferase III, ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3, Sialyltransferase 8C, Sialytransfer reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SIA8C can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:100-500 ELISA: 1:1,000 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the SIA8C st8sia3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SIA8C, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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