Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human endometrial cancer using MBS7045333 at dilution of 1:100)
Rabbit anti-Human SHROOM3 Polyclonal Antibody | anti-SHROOM3 antibody
SHROOM3 Antibody
Gene Names
SHROOM3; SHRM; APXL3; ShrmL; MSTP013
Reactivity
Human
Applications
ELISA, Immunohistochemistry, Immunofluorescence
Purity
>95%, Protein G purified
Synonyms
SHROOM3; Polyclonal Antibody; SHROOM3 Antibody; Protein Shroom3; Shroom-related protein; hShrmL; KIAA1481; SHRML; MSTP013; anti-SHROOM3 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
>95%, Protein G purified
Form/Format
Liquid
Sequence Length
1996
Applicable Applications for anti-SHROOM3 antibody
ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes
IHC: 1:20-1:200
IF: 1:50-1:200
IF: 1:50-1:200
Species
Homo Sapiens (Human)
Research Area
Signal Transduction
Immunogen
Recombinant human Protein Shroom3 protein (1309-1571AA)
Conjugate
Non-conjugated
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-10308 / sc-10311 / sc-10310 / sc-10309
Preparation and Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human endometrial cancer using MBS7045333 at dilution of 1:100)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human endometrial cancer using MBS7045333 at dilution of 1:100)
Immunofluorescence (IF)
(Immunofluorescent analysis of HepG2 cells using MBS7045333 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))
Immunofluorescence (IF)
(Immunofluorescent analysis of HepG2 cells using MBS7045333 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))
Related Product Information for anti-SHROOM3 antibody
Controls cell shape changes in the neuroepithelium during neural tube closure. Induces apical constriction in epithelial cells by promoting the apical accumulation of F-actin and myosin II, and probably by bundling stress fibers. Induces apicobasal cell elongation by redistributing gamma-tubulin and directing the assembly of robust apicobasal microtubule arrays (By similarity).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
protein Shroom3
NCBI Official Synonym Full Names
shroom family member 3
NCBI Official Symbol
SHROOM3
NCBI Official Synonym Symbols
SHRM; APXL3; ShrmL; MSTP013
NCBI Protein Information
protein Shroom3
UniProt Protein Name
Protein Shroom3
Protein Family
UniProt Gene Name
SHROOM3
UniProt Synonym Gene Names
KIAA1481; SHRML; hShrmL
UniProt Entry Name
SHRM3_HUMAN
NCBI Description
This gene encodes a PDZ-domain-containing protein that belongs to a family of Shroom-related proteins. This protein may be involved in regulating cell shape in certain tissues. A similar protein in mice is required for proper neurulation. [provided by RefSeq, Jan 2011]
Uniprot Description
SHRM: a filamentous-actin binding protein. Required for normal neural tube closure and cytoskeletal polarity in developing neuroepithelial cells.
Protein type: Cytoskeletal
Chromosomal Location of Human Ortholog: 4q21.1
Cellular Component: adherens junction; apical junction complex; apical plasma membrane; cytoskeleton
Biological Process: apical protein localization; cell morphogenesis; cellular pigment accumulation; pattern specification process
Research Articles on SHROOM3
Similar Products
Product Notes
The SHROOM3 shroom3 (Catalog #AAA7045333) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SHROOM3 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SHROOM3 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF). IHC: 1:20-1:200 IF: 1:50-1:200. Researchers should empirically determine the suitability of the SHROOM3 shroom3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SHROOM3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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