Rabbit SHP2 Polyclonal Antibody
SHP2, CT (SH2 Domain-containing Protein Tyrosine Phosphatase 2, SHP-2, BPTP3, BPTP-3, CFC, MGC14433, Noonan Syndrome 1, Noonan Syndrome 1 Protein Tyrosine Phosphatase 2C, NS1, Protein Tyrosine Phosphatase 2C, PTP2C, PTP-2C, Protein Tyrosine Phosphatase No
Reactivity
Human, Mouse, Rat
Applications
Western Blot
Purity
Affinity PurifiedPurified by immunoaffinity chromatography.
Synonyms
SHP2; Polyclonal Antibody; CT (SH2 Domain-containing Protein Tyrosine Phosphatase 2; SHP-2; BPTP3; BPTP-3; CFC; MGC14433; Noonan Syndrome 1; Noonan Syndrome 1 Protein Tyrosine Phosphatase 2C; NS1; Protein Tyrosine Phosphatase 2C; PTP2C; PTP-2C; Protein Tyrosine Phosphatase No; Anti -SHP2; anti-SHP2 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human SHP2 at ~68kD in skeletal muscle tissue lysate. Species Crossreactivity: mouse, rat.
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography.
Purified by immunoaffinity chromatography.
Form/Format
Supplied as a liquid in PBS, 0.02% sodium azide.
Applicable Applications for anti-SHP2 antibody
Western Blot (WB)
Application Notes
Suitable for use in Western Blot.
Dilution: Western Blot: 0.5-1ug/ml
Dilution: Western Blot: 0.5-1ug/ml
Immunogen
14aa peptide sequence near the carboxy terminus of human SHP2.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Related Product Information for anti-SHP2 antibody
SHP2 is a 68kD member of the protein tyrosine phosphatase family. SHP2 acts downstream of growth factor receptors and cytoplasmic protein tyrosine kinases which transduce signals from cell surface to the nucleus. The recruitment and activation of SHP2 is mediated through the binding of CD172a to its ligand CD47. SHP2 regulates a variety of cellular processes. These include transcription, embryonic development, cell growth, cell migration, differentiation, mitotic cycle, haematopoiesis and oncogenic transformation. As a result, dysregulation of the SHP2 gene has been linked to LEOPARD, Noonan and Noonan-like syndrome as well as acute myeloid leukaemia. SHP2 is ubiquitously expressed, with highest levels found in heart, brain, and skeletal muscle.
Product Categories/Family for anti-SHP2 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI Official Full Name
shatterproof 2
Similar Products
Product Notes
The SHP2 (Catalog #AAA623249) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SHP2, CT (SH2 Domain-containing Protein Tyrosine Phosphatase 2, SHP-2, BPTP3, BPTP-3, CFC, MGC14433, Noonan Syndrome 1, Noonan Syndrome 1 Protein Tyrosine Phosphatase 2C, NS1, Protein Tyrosine Phosphatase 2C, PTP2C, PTP-2C, Protein Tyrosine Phosphatase No reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's SHP2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Suitable for use in Western Blot. Dilution: Western Blot: 0.5-1ug/ml. Researchers should empirically determine the suitability of the SHP2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SHP2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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