Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using SHP-2 (Phospho-Tyr542) antibody (left) or the same antibody preincubated with with blocking peptide (right))
Rabbit SHP2 Polyclonal Antibody | anti-SHP2 antibody
SHP2 antibody
Applications
Immunohistochemistry, Western Blot
Purity
Purified by immunoaffinity chromatography.
Synonyms
SHP2; Polyclonal Antibody; SHP2 antibody; Rabbit polyclonal SHP2 antibody; Polyclonal SHP2 antibody; Anti-SHP2 antibody; PTP-2C antibody; SHP-2; Tyrosine-protein phosphatase non-receptor type 11 antibody; SHP 2; Phospho Tyr542 antibody; SHP 2 antibody; PTPN11 antibody; Protein-tyrosine phosphatase 2C antibody; SHP-2 antibody; PTP-1D antibody; Protein-tyrosine phosphatase 1D antibody; anti-SHP2 antibody
Host
Rabbit
Clonality
Polyclonal
Purity/Purification
Purified by immunoaffinity chromatography.
Form/Format
Liquid form in PBS buffer (no MG2+ or Ca2+), pH 7.4, 150 mm NaCl,0.02% sodium azide and 50% glycerol.
Concentration
1 mg/ml (varies by lot)
Sequence Length
244
Applicable Applications for anti-SHP2 antibody
Immunohistochemistry (IHC), Western Blot (WB)
Application Notes
IHC: 1:50-1:100
WB: 1:500-1:1000
WB: 1:500-1:1000
Immunogen
SHP2 antibody was raised in Rabbit using the peptide sequence around phosphorylation site of tyrosine 542 (H-E-Y(p)-T-N) derived from Human SHP-2 as the immunogen.
Cross-Reactivity
Human, Mouse, Rat
Preparation and Storage
Store at 4 degree C for short term storage.
Aliquot and store at-20 degree C for long term storage.
Avoid repeated freeze/thaw cycles.
Aliquot and store at-20 degree C for long term storage.
Avoid repeated freeze/thaw cycles.
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using SHP-2 (Phospho-Tyr542) antibody (left) or the same antibody preincubated with with blocking peptide (right))
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using SHP-2 (Phospho-Tyr542) antibody (left) or the same antibody preincubated with with blocking peptide (right))
Western Blot (WB)
(Western Blot analysis of extracts from 293 cells untreated or treated with starvation using SHP-2 (Phospho-Tyr542) antibody)
Western Blot (WB)
(Western Blot analysis of extracts from 293 cells untreated or treated with starvation using SHP-2 (Phospho-Tyr542) antibody)
Related Product Information for anti-SHP2 antibody
SHP2 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration.
Product Categories/Family for anti-SHP2 antibody
NCBI and Uniprot Product Information
NCBI GI #
Molecular Weight
28,006 Da
NCBI Official Full Name
shatterproof 2
UniProt Protein Name
Shatterproof 2
UniProt Gene Name
SHP2
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Product Notes
The SHP2 shp2 (Catalog #AAA5309616) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's SHP2 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), Western Blot (WB). IHC: 1:50-1:100 WB: 1:500-1:1000. Researchers should empirically determine the suitability of the SHP2 shp2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SHP2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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