Rabbit SHO1 Polyclonal Antibody | anti-SHO1 antibody
Rabbit anti-Saccharomyces cerevisiae (strain RM11-1a)(Baker's yeast) SHO1 Polyclonal Antibody
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH7.4
2. 1mL preimmune serum (negative control)
3. 10mg rabbit polyclonal antibody purified by Protein A/G.
2. Antibody titer > 1: 64,000 confirmed by ELISA
3. Western Blot positive for the immunogen protein (Not applicable for synthetic peptide).
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NCBI and Uniprot Product Information
Uniprot Description
Function: Plasma membrane osmosensor that activates the high osmolarity glycerol (HOG) MAPK signaling pathway in response to high osmolarity. Detects changes in external osmolarity and activates PBS2 through the stimulation of STE11 and targets PBS2 to the plasma membrane. PBS2 activation leads to changes in glycerol production that helps to balance the intracellular and external osmotic pressures. Activates also HOG1 in response to heat stress and mediates resistance to oxidative stress. Involved in the regulation of the mating pathway. May be a receptor that feeds into the pseudohyphal growth pathway
By similarity.
Subunit structure: Forms homooligomers
By similarity. Interacts (via the SH3 domain) with PBS2. Interacts with FUS1, STE11, STE50 and RNA polymerase II
By similarity.
Subcellular location: Cell membrane; Multi-pass membrane protein
By similarity. Bud
By similarity. Bud neck
By similarity. Cell projection
By similarity. Note: Localizes at the tip of the mating projection during conjugation
By similarity.
Sequence similarities: Belongs to the SHO1 family.Contains 1 SH3 domain.