Western Blot (WB)
(SHBG Antibody (N-term) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the SHBG antibody detected the SHBG protein (arrow).)
Rabbit anti-Human SHBG Polyclonal Antibody | anti-SHBG antibody
SHBG Antibody (N-term)
Western Blot (WB)
(SHBG Antibody (N-term) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the SHBG antibody detected the SHBG protein (arrow).)
Western Blot (WB)
(SHBG Antibody (N-term) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the SHBG antibody detected the SHBG protein (arrow).)
described as a plasma protein secreted by the liver but is now
thought to participate in the regulation of steroid responses. The
encoded protein binds each steroid molecule as a dimer formed from
identical or nearly identical monomers. The use of alternate
promoters and alternatively spliced transcripts have been
described. Multiple transcript variants encoding different isoforms
have been found for this gene.
Xita, N., et al. Exp. Clin. Endocrinol. Diabetes (2010) In press :
Diaz, M., et al. Fertil. Steril. (2010) In press :
Hatzi, E., et al. Gynecol. Endocrinol. (2010) In press :
Iwasaki, M., et al. Nutr Cancer 62(4):466-475(2010)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a steroid binding protein that was first described as a plasma protein secreted by the liver but is now thought to participate in the regulation of steroid responses. The encoded protein transports androgens and estrogens in the blood, binding each steroid molecule as a dimer formed from identical or nearly identical monomers. Polymorphisms in this gene have been associated with polycystic ovary syndrome and type 2 diabetes mellitus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
Uniprot Description
SHBG: Functions as an androgen transport protein, but may also be involved in receptor mediated processes. Each dimer binds one molecule of steroid. Specific for 5-alpha-dihydrotestosterone, testosterone, and 17-beta-estradiol. Regulates the plasma metabolic clearance rate of steroid hormones by controlling their plasma concentration. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 17p13.1
Cellular Component: extracellular region
Molecular Function: androgen binding
Biological Process: primary spermatocyte growth
Research Articles on SHBG
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Product Notes
The SHBG shbg (Catalog #AAA9213263) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 69-96. The SHBG Antibody (N-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SHBG can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the SHBG shbg for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SHBG, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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