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Western Blot (WB) (Western blot analysis of extracts from 3T3 cells, using SGK269 antibody.)

Rabbit anti-Human, Mouse SGK269 Polyclonal Antibody | anti-SGK269 antibody

SGK269 Antibody

Gene Names
PEAK1; SGK269
Reactivity
Human, Mouse
Applications
Western Blot
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
SGK269; Polyclonal Antibody; SGK269 Antibody; Pseudopodium-enriched atypical kinase 1; Sugen kinase 269; Tyrosine-protein kinase SgK269; PEAK1; KIAA2002; anti-SGK269 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Specificity
The antibody detects endogenous levels of total SGK269 protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1.0 mg/ml (varies by lot)
Sequence Length
1746
Applicable Applications for anti-SGK269 antibody
Western Blot (WB)
Application Notes
Western blotting: 1:500~1:3000
Immunogen Type
Peptide
Immunogen Description
Synthesized peptide derived from N-terminal of human SGK269.
Target Name
SGK269
Preparation and Storage
Store at -20 degree C

Western Blot (WB)

(Western blot analysis of extracts from 3T3 cells, using SGK269 antibody.)

Western Blot (WB) (Western blot analysis of extracts from 3T3 cells, using SGK269 antibody.)
Related Product Information for anti-SGK269 antibody
Tyrosine kinase that may play a role in cell spreading and migration on fibronectin. May directly or indirectly affect phosphorylation levels of cytoskeleton-associated proteins MAPK1/ERK and PXN.Zody M.C., Nature 440:671-675(2006).Jikuya H., Submitted (JAN-2002) to the EMBL/GenBank/DDBJ databases.Ohara O., DNA Res. 9:47-57(2002).
Product Categories/Family for anti-SGK269 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
193,106 Da
NCBI Official Full Name
pseudopodium-enriched atypical kinase 1
NCBI Official Synonym Full Names
pseudopodium-enriched atypical kinase 1
NCBI Official Symbol
PEAK1
NCBI Official Synonym Symbols
SGK269
NCBI Protein Information
pseudopodium-enriched atypical kinase 1
UniProt Protein Name
Pseudopodium-enriched atypical kinase 1
UniProt Gene Name
PEAK1
UniProt Synonym Gene Names
KIAA2002
UniProt Entry Name
PEAK1_HUMAN

NCBI Description

This gene encodes a non-receptor tyrosine kinase that is a member of the new kinase family three (NFK3) family. In migrating cells, the encoded protein is associated with the actin cytoskeleton and focal adhesions and promotes developing focal adhesion elongation. This protein may play a role in the regulation of cell migration, proliferation and cancer metastasis. [provided by RefSeq, Mar 2014]

Uniprot Description

PEAK1: Tyrosine kinase that may play a role in cell spreading and migration on fibronectin. May directly or indirectly affect phosphorylation levels of cytoskeleton-associated proteins MAPK1/ERK and PXN. Belongs to the protein kinase superfamily.

Protein type: Kinase, protein; EC 2.7.10.2; Protein kinase, Other; Protein kinase, Ser/Thr (non-receptor); Other group; NKF3 family

Chromosomal Location of Human Ortholog: 15q24.3

Cellular Component: nucleoplasm; focal adhesion; cytoplasm; plasma membrane; actin cytoskeleton

Molecular Function: protein binding; non-membrane spanning protein tyrosine kinase activity; ATP binding

Biological Process: cell migration; peptidyl-tyrosine phosphorylation; protein amino acid autophosphorylation

Research Articles on SGK269

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Product Notes

The SGK269 peak1 (Catalog #AAA9409738) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SGK269 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's SGK269 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Western blotting: 1:500~1:3000. Researchers should empirically determine the suitability of the SGK269 peak1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SGK269, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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