Western Blot (WB)
(Western Blot analysis of SFXN1 in PC-3, MCF-7 and K562 cell, Human cerebrum tissue, Hepg2 cell, Human fetal liver tissue in order using SFXN1 Rabbit pAb at dilution 1/200)
Rabbit SFXN1 Polyclonal Antibody | anti-SFXN1 antibody
SFXN1 Rabbit pAb
Reactivity
Human, Mouse, Rat
Applications
Western Blot
Purity
Affinity purified
Synonyms
SFXN1; Polyclonal Antibody; SFXN1 Rabbit pAb; sideroflexin 1; anti-SFXN1 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity purified
Form/Format
pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Concentration
0.5mg/ml (varies by lot)
Applicable Applications for anti-SFXN1 antibody
Western Blot (WB)
Application Notes
WB: 1:200-1:1000
Immunogen
Fusion protein of human SFXN1
Conjugation
Unconjugated
Modification
Unmodified
Preparation and Storage
Store at 4 degree C for short term. Store at -20 degree C for long term. Avoid freeze/thaw cycle.
Western Blot (WB)
(Western Blot analysis of SFXN1 in PC-3, MCF-7 and K562 cell, Human cerebrum tissue, Hepg2 cell, Human fetal liver tissue in order using SFXN1 Rabbit pAb at dilution 1/200)
Western Blot (WB)
(Western Blot analysis of SFXN1 in PC-3, MCF-7 and K562 cell, Human cerebrum tissue, Hepg2 cell, Human fetal liver tissue in order using SFXN1 Rabbit pAb at dilution 1/200)
Related Product Information for anti-SFXN1 antibody
The sideroflexin (SFXN) family is comprised of SFXN1, SFXN2, SFXN3, SFXN4 and SFXN5. SFXN1, also designated tricarboxylate carrier protein TCC, is the most highly characterized family member. The ubiquitously expressed SFXN1 protein resides as an integral protein of the mitochondrial inner membrane. It functions as an essential component of the shuttle system that transports mitochondrial acetyl-CoA into the cytosol, where lipogenesis occurs. The SFXN1 gene is mutated in flexed-tail (f/f) mice, which display axial skeletal abnormalities and a transient embryonic and neonatal anemia characterized by pathologic intramitochondiral iron deposits in erythrocytes. Therefore, SFXN1 is also thought to facilitate the transport of a component required for iron utilization into mitochondria. All SFXN family members show expression in pancreatic islet cells. SFXN5 displays a citrate transport activity and is primarily expressed in brain.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
322
NCBI Official Full Name
Sideroflexin-1
NCBI Official Synonym Full Names
sideroflexin 1
NCBI Official Symbol
SFXN1
NCBI Protein Information
sideroflexin-1; TCC; tricarboxylate carrier protein
UniProt Protein Name
Sideroflexin-1
Protein Family
UniProt Gene Name
SFXN1
UniProt Synonym Gene Names
TCC
UniProt Entry Name
SFXN1_HUMAN
Uniprot Description
SFXN1: Might be involved in the transport of a component required for iron utilization into or out of the mitochondria. Belongs to the sideroflexin family.
Protein type: Mitochondrial; Membrane protein, multi-pass; Membrane protein, integral
Chromosomal Location of Human Ortholog: 5q35.3
Cellular Component: mitochondrion; mitochondrial inner membrane; integral to membrane
Molecular Function: ion transmembrane transporter activity
Biological Process: iron ion homeostasis; erythrocyte differentiation; iron ion transport
Research Articles on SFXN1
Similar Products
Product Notes
The SFXN1 sfxn1 (Catalog #AAA4759093) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SFXN1 Rabbit pAb reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's SFXN1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:200-1:1000. Researchers should empirically determine the suitability of the SFXN1 sfxn1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SFXN1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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