Western Blot (WB)
(Western blot analysis SFRS6 using HT29 whole cell lysates)
Rabbit SFRS6 Polyclonal Antibody | anti-SFRS6 antibody
SFRS6 Antibody
Gene Names
SRSF6; B52; SFRS6; SRP55; HEL-S-91
Reactivity
Human, Mouse, Rat
Applications
Western Blot, ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Synonyms
SFRS6; Polyclonal Antibody; SFRS6 Antibody; arginine/serine-rich 6; B52; Epididymis secretory protein Li 91; fc17h09; HEL S 91; MGC128807; MGC5045; Pre mRNA splicing factor SRP55; Pre-mRNA-splicing factor SRP55; Serine/arginine-rich splicing factor 6; Splicing factor; Splicing factor arginine/serine rich 55 kDa; Splicing factor arginine/serine rich 6; SR splicing factor 6; SRP55; SRSF6; SRSF6_HUMAN; wu:faa54g02; wu:fc17h09; zgc:103497; anti-SFRS6 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
SFRS6 antibody detects endogenous levels of total SFRS6
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Form/Format
Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Sequence Length
344
Applicable Applications for anti-SFRS6 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:1000-3000
Immunogen
A synthesized peptide derived from human SFRS6
Subcellular Location
Nucleus
Predicted Cross Reactivity
Chicken
Similarity
Chicken (86%)
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
Western Blot (WB)
(Western blot analysis SFRS6 using HT29 whole cell lysates)
Western Blot (WB)
(Western blot analysis SFRS6 using HT29 whole cell lysates)
Related Product Information for anti-SFRS6 antibody
Function: Plays a role in constitutive splicing and modulates the selection of alternative splice sites. Plays a role in the alternative splicing of MAPT/Tau exon 10. Binds to alternative exons of TNC pre-mRNA and promotes the expression of alternatively spliced TNC. Plays a role in wound healing and in the regulation of keratinocyte differentiation and proliferation via its role in alternative splicing.
Subunit Structure: Binds SREK1/SFRS12. Interacts with DYRK1A.
Post-translational Modifications: Extensively phosphorylated on serine residues in the RS domain. Phosphorylated by DYRK1A, probably in the RS domain. Phosphorylation by DYRK1A modulates alternative splice site selection and inhibits the expression of MAPT/Tau exon 10.
Similarity: Belongs to the splicing factor SR family.
Subunit Structure: Binds SREK1/SFRS12. Interacts with DYRK1A.
Post-translational Modifications: Extensively phosphorylated on serine residues in the RS domain. Phosphorylated by DYRK1A, probably in the RS domain. Phosphorylation by DYRK1A modulates alternative splice site selection and inhibits the expression of MAPT/Tau exon 10.
Similarity: Belongs to the splicing factor SR family.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Observed: 40 kDa
Predicted: 40 kDa
Predicted: 40 kDa
NCBI Official Full Name
serine/arginine-rich splicing factor 6
NCBI Official Synonym Full Names
serine and arginine rich splicing factor 6
NCBI Official Symbol
SRSF6
NCBI Official Synonym Symbols
B52; SFRS6; SRP55; HEL-S-91
NCBI Protein Information
serine/arginine-rich splicing factor 6
UniProt Protein Name
Serine/arginine-rich splicing factor 6
UniProt Gene Name
SRSF6
UniProt Synonym Gene Names
SFRS6; SRP55
NCBI Description
The protein encoded by this gene is involved in mRNA splicing and may play a role in the determination of alternative splicing. The encoded nuclear protein belongs to the splicing factor SR family and has been shown to bind with and modulate another member of the family, SFRS12. Alternative splicing results in multiple transcript variants. In addition, two pseudogenes, one on chromosome 17 and the other on the X chromosome, have been found for this gene.[provided by RefSeq, Sep 2010]
Uniprot Description
Plays a role in constitutive splicing and modulates the selection of alternative splice sites. Plays a role in the alternative splicing of MAPT/Tau exon 10. Binds to alternative exons of TNC pre-mRNA and promotes the expression of alternatively spliced TNC. Plays a role in wound healing and in the regulation of keratinocyte differentiation and proliferation via its role in alternative splicing.
Research Articles on SFRS6
Similar Products
Product Notes
The SFRS6 srsf6 (Catalog #AAA9609141) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SFRS6 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's SFRS6 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:1000-3000. Researchers should empirically determine the suitability of the SFRS6 srsf6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SFRS6, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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