Western Blot (WB)
(Western blot analysis of SFRS5 antibody (Center Y85) in NCI-H460 cell line lysates (35ug/lane). SFRS5 (arrow) was detected using the purified Pab.)
Rabbit anti-Human SFRS5 Polyclonal Antibody | anti-SFRS5 antibody
SFRS5, ID (Y85) (Splicing Factor, Arginine/Serine-rich 5, Pre-mRNA-splicing Factor SRP40, Delayed-early Protein HRS, SRP40, HRS) (MaxLight 750)
FLISA: 1:1,000
Applications are based on unconjugated antibody.
Western Blot (WB)
(Western blot analysis of SFRS5 antibody (Center Y85) in NCI-H460 cell line lysates (35ug/lane). SFRS5 (arrow) was detected using the purified Pab.)
Western Blot (WB)
(Western blot analysis of SFRS5 antibody (Center Y85) in NCI-H460 cell line lysates (35ug/lane). SFRS5 (arrow) was detected using the purified Pab.)
Flow Cytometry (FC/FACS)
(SFRS5 Antibody (Center Y85) flow cytometric analysis of NCI-H292 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
Flow Cytometry (FC/FACS)
(SFRS5 Antibody (Center Y85) flow cytometric analysis of NCI-H292 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]
Uniprot Description
SFRS5: Plays a role in constitutive splicing and can modulate the selection of alternative splice sites. Belongs to the splicing factor SR family. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: RNA-binding; RNA processing; Spliceosome
Chromosomal Location of Human Ortholog: 14q24
Cellular Component: nucleoplasm; cytoplasm; nucleolus; nuclear speck; nucleus
Molecular Function: RS domain binding; protein binding; nucleotide binding
Biological Process: transcription from RNA polymerase II promoter; nuclear mRNA splicing, via spliceosome; mRNA splice site selection; mRNA export from nucleus; regulation of cell cycle; RNA splicing; response to wounding; gene expression; mRNA 3'-end processing; mRNA processing; termination of RNA polymerase II transcription
Research Articles on SFRS5
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Product Notes
The SFRS5 srsf5 (Catalog #AAA6500555) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SFRS5, ID (Y85) (Splicing Factor, Arginine/Serine-rich 5, Pre-mRNA-splicing Factor SRP40, Delayed-early Protein HRS, SRP40, HRS) (MaxLight 750) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SFRS5 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), FLISA. WB: 1:50-1:100 FLISA: 1:1,000 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the SFRS5 srsf5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SFRS5, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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