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Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue using at dilution 1/30.)

Rabbit anti-Human SETD3 Polyclonal Antibody | anti-SETD3 antibody

SETD3 Antibody

Gene Names
SETD3; C14orf154
Reactivity
Human
Applications
Immunohistochemistry
Purity
Antigen Affinity Purification
Synonyms
SETD3; Polyclonal Antibody; SETD3 Antibody; C14orf154; anti-SETD3 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
The antibody detects endogenous levels of total SETD3 protein.
Purity/Purification
Antigen Affinity Purification
Form/Format
Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
Concentration
1.3 mg/ml (varies by lot)
Sequence Length
594
Applicable Applications for anti-SETD3 antibody
Immunohistochemistry (IHC)
Application Notes
Immunohistochemistry: 1:25-1:100
Immunogen
Fusion protein of human SETD3
Immunogen Type
Protein
Preparation and Storage
Store at -20 degree C

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue using at dilution 1/30.)

Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue using at dilution 1/30.)

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded Human ovarian cancer tissue using at dilution 1/30.)

Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded Human ovarian cancer tissue using at dilution 1/30.)
Related Product Information for anti-SETD3 antibody
Histone methyltransferase that methylates 'Lys-4' and 'Lys-36' of histone H3 (H3K4me and H3K36me). Acts as a transcriptional activator. Plays an important role in the transcriptional regulation of muscle cell differentiation via interaction with MYOD1.
Product Categories/Family for anti-SETD3 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
32,540 Da
NCBI Official Full Name
histone-lysine N-methyltransferase setd3 isoform a
NCBI Official Synonym Full Names
SET domain containing 3
NCBI Official Symbol
SETD3
NCBI Official Synonym Symbols
C14orf154
NCBI Protein Information
histone-lysine N-methyltransferase setd3
UniProt Protein Name
Histone-lysine N-methyltransferase setd3
UniProt Gene Name
SETD3
UniProt Synonym Gene Names
C14orf154
UniProt Entry Name
SETD3_HUMAN

Uniprot Description

SETD3: Histone methyltransferase that methylates 'Lys-36' of histone H3 (H3K36me). H3 'Lys-36' methylation represents a specific tag for epigenetic transcriptional activation. Belongs to the SETD3 family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 2.1.1.43; Methyltransferase; Methyltransferase, protein lysine

Chromosomal Location of Human Ortholog: 14q32.2

Cellular Component: nuclear chromatin; nucleoplasm

Molecular Function: histone lysine N-methyltransferase activity (H3-K36 specific); histone lysine N-methyltransferase activity (H3-K4 specific); histone-lysine N-methyltransferase activity; transcription coactivator activity

Biological Process: histone H3-K36 methylation; histone H3-K4 methylation; peptidyl-lysine di-methylation; peptidyl-lysine mono-methylation; peptidyl-lysine tri-methylation; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent

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Product Notes

The SETD3 setd3 (Catalog #AAA9415555) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SETD3 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SETD3 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC). Immunohistochemistry: 1:25-1:100. Researchers should empirically determine the suitability of the SETD3 setd3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SETD3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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