Rabbit anti-Mouse, Human Serpinh1 Polyclonal Antibody | anti-Serpinh1 antibody
Serpinh1 Antibody, HRP conjugated
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
NCBI and Uniprot Product Information
Uniprot Description
SERPINH1: Binds specifically to collagen. Could be involved as a chaperone in the biosynthetic pathway of collagen. Defects in SERPINH1 are the cause of osteogenesis imperfecta type 10 (OI10). A connective tissue disorder characterized by bone fragility, low bone mass, bowing of limbs due to multiple fractures, short limb dwarfism and blue sclerae. Belongs to the serpin family.
Cellular Component: cytoplasm; endoplasmic reticulum; ER-Golgi intermediate compartment; extracellular space; lipid raft
Molecular Function: collagen binding; protein binding; serine-type endopeptidase inhibitor activity; unfolded protein binding
Biological Process: collagen biosynthetic process; collagen fibril organization; protein maturation