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Immunohistochemistry (IHC) (Human Colon, Vessel: Formalin-Fixed, Paraffin-Embedded (FFPE))

Sheep anti-Human SERPING1/C1 Inhibitor Polyclonal Antibody | anti-SERPING1 antibody

Anti-SERPING1/C1 Inhibitor Antibody

Gene Names
SERPING1; C1IN; C1NH; HAE1; HAE2; C1INH
Reactivity
Human
Applications
ELISA, Flow Cytometry, Functional Assay, Immunodiffusion, Immunohistochemistry, Immunoprecipitation, Western Blot
Purity
Immunoaffinity Purified
Synonyms
SERPING1/C1 Inhibitor; Polyclonal Antibody; Anti-SERPING1/C1 Inhibitor Antibody; Goat Polyclonal (IgG) to Human SERPING1/C1 Inhibitor; SERPING1; C1-inhibiting factor; C1IN; C1 Inh; C1-INH; C1INH; C1NH; C1 Inhibitor; HAE1; HAE2; Plasma protease C1 inhibitor; C1 esterase inhibitor; Serpin G1; anti-SERPING1 antibody
Ordering
For Research Use Only!
Host
Sheep
Reactivity
Human
Clonality
Polyclonal
Specificity
Human C1 Inhibitor
Purity/Purification
Immunoaffinity Purified
Form/Format
10 mM sodium phosphate, 0.15 M sodium chloride, pH 7.2, 0.05% sodium azide.
Sequence Length
500
Applicable Applications for anti-SERPING1 antibody
ELISA (EIA), Flow Cytometry (FC/FACS), Immunodiffusion (ID), Immunohistochemistry (IHC) Paraffin, Immunoprecipitation (IP), Western Blot (WB)
Application Notes
IHC-P: 5 ug/ml
Immunogen
Human C1 Inhibitor.
Conjugation
Unconjugated
Preparation and Storage
Store at 2 degree C to 8 degree C.

Immunohistochemistry (IHC)

(Human Colon, Vessel: Formalin-Fixed, Paraffin-Embedded (FFPE))

Immunohistochemistry (IHC) (Human Colon, Vessel: Formalin-Fixed, Paraffin-Embedded (FFPE))
Related Product Information for anti-SERPING1 antibody
Activation of the C1 complex is under control of the C1-inhibitor. It forms a proteolytically inactive stoichiometric complex with the C1r orC1s proteases. May play a potentially crucial role in regulating important physiological pathways including complement activation, blood coagulation, fibrinolysis and the generation of kinins. Very efficient inhibitor of FXIIa. Inhibits chymotrypsin and kallikrein.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
710
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
55,769 Da
NCBI Official Full Name
plasma protease C1 inhibitor
NCBI Official Synonym Full Names
serpin family G member 1
NCBI Official Symbol
SERPING1
NCBI Official Synonym Symbols
C1IN; C1NH; HAE1; HAE2; C1INH
NCBI Protein Information
plasma protease C1 inhibitor
UniProt Protein Name
Plasma protease C1 inhibitor
UniProt Gene Name
SERPING1
UniProt Synonym Gene Names
C1IN; C1NH; C1 Inh; C1Inh

NCBI Description

This gene encodes a highly glycosylated plasma protein involved in the regulation of the complement cascade. Its protein inhibits activated C1r and C1s of the first complement component and thus regulates complement activation. Deficiency of this protein is associated with hereditary angioneurotic oedema (HANE). Alternative splicing results in multiple transcript variants encoding the same isoform. [provided by RefSeq, Jul 2008]

Uniprot Description

Activation of the C1 complex is under control of the C1-inhibitor. It forms a proteolytically inactive stoichiometric complex with the C1r or C1s proteases. May play a potentially crucial role in regulating important physiological pathways including complement activation, blood coagulation, fibrinolysis and the generation of kinins. Very efficient inhibitor of FXIIa. Inhibits chymotrypsin and kallikrein.

Research Articles on SERPING1

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Product Notes

The SERPING1 serping1 (Catalog #AAA2401381) is an Antibody produced from Sheep and is intended for research purposes only. The product is available for immediate purchase. The Anti-SERPING1/C1 Inhibitor Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SERPING1/C1 Inhibitor can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Flow Cytometry (FC/FACS), Immunodiffusion (ID), Immunohistochemistry (IHC) Paraffin, Immunoprecipitation (IP), Western Blot (WB). IHC-P: 5 ug/ml. Researchers should empirically determine the suitability of the SERPING1 serping1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SERPING1/C1 Inhibitor, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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