Western Blot (WB)
(Western Blot analysis of Human fetal liver tissue using SERPINB3 Polyclonal Antibody at dilution of 1:200)
Rabbit SERPINB3 Polyclonal Antibody | anti-SERPINB3 antibody
SERPINB3 Polyclonal Antibody
Gene Names
SERPINB3; SCC; T4-A; SCCA1; SCCA-1; HsT1196; SCCA-PD
Reactivity
Human, Mouse, Rat
Applications
ELISA, Western Blot
Purity
Antigen affinity purification
Synonyms
SERPINB3; Polyclonal Antibody; SERPINB3 Polyclonal Antibody; SCC; T4-A; SCCA1; SCCA-1; HsT1196; SCCA-PD; anti-SERPINB3 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen affinity purification
Concentration
1.3mg/mL (varies by lot)
Sequence Length
390
Applicable Applications for anti-SERPINB3 antibody
ELISA (EIA), Western Blot (WB)
Application Notes
WB: 1:500-1:2000
Immunogen
Recombinant protein of human SERPINB3
Buffer
PBS with 0.05% sodium azide, 50% glycerol, pH7.3
Preparation and Storage
Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.
Western Blot (WB)
(Western Blot analysis of Human fetal liver tissue using SERPINB3 Polyclonal Antibody at dilution of 1:200)
Western Blot (WB)
(Western Blot analysis of Human fetal liver tissue using SERPINB3 Polyclonal Antibody at dilution of 1:200)
Related Product Information for anti-SERPINB3 antibody
SERPINB3(serpin peptidase inhibitor, clade B (ovalbumin), member 3), also known as SCCA1, increase in advancing stages of some cervical, lung, esophageal and head and neck cancers). Human chromosome position 18q21. 3 contains a cluster of serpins, including a tandem duplication of the SCCA gene, plasminogen activator inhibitor type 2, and maspin. SCCA is transcribed by two nearly identical genes (SCCA1 and SCCA2), and is mainly produced as SCCA1. The human SCCA1 gene encodes a 390 amino acid protein that was originally isolated from a metastatic cervical squamous cell carcinoma.
Product Categories/Family for anti-SERPINB3 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
38,550 Da
NCBI Official Full Name
serpin B3
NCBI Official Synonym Full Names
serpin peptidase inhibitor, clade B (ovalbumin), member 3
NCBI Official Symbol
SERPINB3
NCBI Official Synonym Symbols
SCC; T4-A; SCCA1; SCCA-1; HsT1196; SCCA-PD
NCBI Protein Information
serpin B3; protein T4-A; serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 3; squamous cell carcinoma antigen 1
UniProt Protein Name
Serpin B3
Protein Family
UniProt Gene Name
SERPINB3
UniProt Synonym Gene Names
SCCA; SCCA1; SCCA-1
UniProt Entry Name
SPB3_HUMAN
Uniprot Description
SERPINB3: May act as a protease inhibitor to modulate the host immune response against tumor cells. Belongs to the serpin family. Ov-serpin subfamily. 2 isoforms of the human protein are produced by alternative splicing.
Chromosomal Location of Human Ortholog: 18q21.3
Cellular Component: extracellular space; cytoplasm; cytoplasmic vesicle; nucleus; vesicle
Molecular Function: serine-type endopeptidase inhibitor activity; viral receptor activity; protease binding; cysteine protease inhibitor activity
Biological Process: negative regulation of proteolysis; negative regulation of JNK activity; entry of virus into host cell; positive regulation of cell proliferation; negative regulation of catalytic activity; negative regulation of peptidase activity; positive regulation of cell migration
Research Articles on SERPINB3
Similar Products
Product Notes
The SERPINB3 serpinb3 (Catalog #AAA2524790) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SERPINB3 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's SERPINB3 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). WB: 1:500-1:2000. Researchers should empirically determine the suitability of the SERPINB3 serpinb3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SERPINB3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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