Rabbit anti-Human SERINC5 Polyclonal Antibody | anti-SERINC5 antibody
SERINC5 Antibody FITC-Conjugated
Gene Names
SERINC5; TPO1; C5orf12
Reactivity
Human
Applications
ELISA, Immunoprecipitation, Western Blot
Synonyms
SERINC5; Polyclonal Antibody; SERINC5 Antibody FITC-Conjugated; C5orf12; SERC5_HUMAN; Serine incorporator 5; TPO1 antibody; anti-SERINC5 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Form/Format
FITC-Conjugated
Concentration
0.5 ug/ul in antibody stabilization buffer (varies by lot)
Sequence Length
543
Applicable Applications for anti-SERINC5 antibody
ELISA (EIA), Immunoprecipitation (IP), Western Blot (WB)
Application Notes
ELISA: 1:10,000
Immunoprecipitation: 1:200
Western Blot: 1:500
Immunoprecipitation: 1:200
Western Blot: 1:500
Immunogen
Synthetic peptide taken within amino acid region 270-320 on human Serine incorporator 5 protein.
Immunoglobulin
IgG
Expression
Highly expressed in placenta, skeletal muscle, spleen, thymus, testis and peripheral leukocyte and is expressed weakly in the heart, liver and fetal brain.
Molecular Function
L-serine transmembrane transporter activity
Structure
Belongs to the TDE1 family
Subcellular Location
Cell membrane; Multi-pass membrane
Preparation and Storage
-20 degree C for long term storage
Related Product Information for anti-SERINC5 antibody
FITC-Conjugated Serine incorporator 5 Antibody
Restriction factor required to restrict infectivity of gammaretroviruses, such as HIV-1: acts by inhibiting early step of viral infection and impairing the ability of the viral particle to translocate its content to the cytoplasm (PubMed:26416733, PubMed:26416734). Enhances the incorporation of serine into phosphatidylserine and sphingolipids. May play a role in providing serine molecules for the formation of myelin glycosphingolipids in oligodendrocytes (By similarity).
Restriction factor required to restrict infectivity of gammaretroviruses, such as HIV-1: acts by inhibiting early step of viral infection and impairing the ability of the viral particle to translocate its content to the cytoplasm (PubMed:26416733, PubMed:26416734). Enhances the incorporation of serine into phosphatidylserine and sphingolipids. May play a role in providing serine molecules for the formation of myelin glycosphingolipids in oligodendrocytes (By similarity).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
51,335 Da
NCBI Official Full Name
serine incorporator 5 isoform X1
NCBI Official Synonym Full Names
serine incorporator 5
NCBI Official Symbol
SERINC5
NCBI Official Synonym Symbols
TPO1; C5orf12
NCBI Protein Information
serine incorporator 5
UniProt Protein Name
Serine incorporator 5
Protein Family
UniProt Gene Name
SERINC5
UniProt Entry Name
SERC5_HUMAN
Uniprot Description
SERINC5: Enhances the incorporation of serine into phosphatidylserine and sphingolipids. May play a role in providing serine molecules for the formation of myelin glycosphingolipids in oligodendrocytes. Belongs to the TDE1 family. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 5q14.1
Cellular Component: Golgi apparatus; integral to membrane; myelin sheath; plasma membrane
Molecular Function: L-serine transmembrane transporter activity
Biological Process: defense response to virus; detection of virus; innate immune response; L-serine transport; myelination; phosphatidylserine metabolic process; phospholipid biosynthetic process; sphingolipid metabolic process; viral reproduction
Research Articles on SERINC5
Similar Products
Product Notes
The SERINC5 serinc5 (Catalog #AAA544829) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SERINC5 Antibody FITC-Conjugated reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SERINC5 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunoprecipitation (IP), Western Blot (WB). ELISA: 1:10,000 Immunoprecipitation: 1:200 Western Blot: 1:500. Researchers should empirically determine the suitability of the SERINC5 serinc5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SERINC5, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
