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Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human kidney using MBS1499471 at dilution 1:100)

Rabbit anti-Human Semenogelin-1 Polyclonal Antibody | anti-SEMG1 antibody

Rabbit anti-human Semenogelin-1 polyclonal Antibody(SEMG1)

Gene Names
SEMG1; SGI; SEMG; CT103; dJ172H20.2
Reactivity
Human
Applications
ELISA, Immunohistochemistry
Purity
Antigen Affinity Purified
Synonyms
Semenogelin-1; Polyclonal Antibody; Rabbit anti-human Semenogelin-1 polyclonal Antibody(SEMG1); Semenogelin I; SGI; SEMG1; SEMG; anti-SEMG1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purified
Sequence Length
462
Applicable Applications for anti-SEMG1 antibody
ELISA (EIA), Immunohistochemistry (IHC)
Application Notes
Recommended dilution: IHC:1:20-1:200
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Conjugate
Non-conjugated
Immunogen
Recombinant human Semenogelin-1 protein (24-310aa)
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-34718 / sc-34717 / sc-34716 / sc-34719 / sc-33819
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human kidney using MBS1499471 at dilution 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human kidney using MBS1499471 at dilution 1:100)
Related Product Information for anti-SEMG1 antibody
Predominant protein in semen. It participates in the formation of a gel matrix entrapping the accessory gland secretions and ejaculated spermatozoa. Fragments of semenogelin and/or fragments of the related proteins may contribute to the activation of progressive sperm movements as the gel-forming proteins are fragmented by KLK3/PSA. Alpha-inhibin-92 and alpha-inhibin-31, derived from the proteolytic degradation of semenogelin, inhibit the secretion of pituitary follicle-stimulating hormone.1 Publication

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
45,322 Da
NCBI Official Full Name
semenogelin-1 preproprotein
NCBI Official Synonym Full Names
semenogelin I
NCBI Official Symbol
SEMG1
NCBI Official Synonym Symbols
SGI; SEMG; CT103; dJ172H20.2
NCBI Protein Information
semenogelin-1
UniProt Protein Name
Semenogelin-1
Protein Family
UniProt Gene Name
SEMG1
UniProt Synonym Gene Names
SEMG; SGI
UniProt Entry Name
SEMG1_HUMAN

NCBI Description

The protein encoded by this gene is the predominant protein in semen. The encoded secreted protein is involved in the formation of a gel matrix that encases ejaculated spermatozoa. The prostate-specific antigen (PSA) protease processes this protein into smaller peptides, with each possibly having a separate function. The proteolysis process breaks down the gel matrix and allows the spermatozoa to move more freely. The antimicrobial peptide SgI-29 is an antimicrobial peptide with antibacterial activity. [provided by RefSeq, Nov 2014]

Uniprot Description

SEMG1: Predominant protein in semen. It participates in the formation of a gel matrix entrapping the accessory gland secretions and ejaculated spermatozoa. Fragments of semenogelin and/or fragments of the related proteins may contribute to the activation of progressive sperm movements as the gel-forming proteins are fragmented by KLK3/PSA. Belongs to the semenogelin family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Cancer Testis Antigen (CTA); Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 20q12-q13.2

Cellular Component: extracellular region; extracellular space; nucleus; protein complex; secretory granule

Molecular Function: metal ion binding; protein binding; structural molecule activity

Biological Process: antibacterial humoral response; cellular protein metabolic process; coagulation; insemination; protein heterooligomerization

Research Articles on SEMG1

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Product Notes

The SEMG1 semg1 (Catalog #AAA1499471) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti-human Semenogelin-1 polyclonal Antibody(SEMG1) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Semenogelin-1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC). Recommended dilution: IHC:1:20-1:200. Researchers should empirically determine the suitability of the SEMG1 semg1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Semenogelin-1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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