Western Blot (WB)
(Western blot analysis SEMA4C using HeLa whole cell lysates)
Rabbit anti-Human SEMA4C Polyclonal Antibody | anti-SEMA4C antibody
SEMA4C Antibody
Gene Names
SEMA4C; SEMAF; SEMAI; SEMACL1; M-SEMA-F
Reactivity
Human
Applications
Western Blot, ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Synonyms
SEMA4C; Polyclonal Antibody; SEMA4C Antibody; KIAA1739; M-SEMA-F; S4c; SEM4C_HUMAN; Sema domain; immunoglobulin domain (Ig); transmembrane domain (TM) and short cytoplasmic domain; (semaphorin) 4C; SEMACL1; SEMAF; SEMAI; Semaphorin-4C; UNQ5855/PRO34487; anti-SEMA4C antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
SEMA4C antibody detects endogenous levels of total SEMA4C
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Form/Format
Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Sequence Length
833
Applicable Applications for anti-SEMA4C antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:1000-3000
Immunogen
A synthesized peptide derived from human SEMA4C
Subcellular Location
Cell Junction > Synapse > Postsynaptic Cell Membrane > Postsynaptic Density. Cytoplasmic Vesicle > Secretory Vesicle > Synaptic Vesicle Membrane.
Predicted Cross Reactivity
Pig, Bovine, Horse, Sheep, Rabbit
Similarity
Pig (90%), Bovine (100%), Horse (100%), Sheep (100%), Rabbit (100%)
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
Western Blot (WB)
(Western blot analysis SEMA4C using HeLa whole cell lysates)
Western Blot (WB)
(Western blot analysis SEMA4C using HeLa whole cell lysates)
Related Product Information for anti-SEMA4C antibody
Function: Cell surface receptor for PLXNB2 that plays an important role in cell-cell signaling. PLXNB2 binding promotes downstream activation of RHOA and phosphorylation of ERBB2 at 'Tyr-1248'. Required for normal brain development, axon guidance and cell migration (By similarity). Probable signaling receptor which may play a role in myogenic differentiation through activation of the stress-activated MAPK cascade.
Subunit Structure: Interacts (via the PDZ-binding motif) with GIPC (via the PDZ domain) (By similarity). Interacts with NCDN (By similarity). Interacts (via the PDZ-binding motif) with DLG4. Interacts with PLXNB2 (By similarity).
Similarity: Belongs to the semaphorin family.
Subunit Structure: Interacts (via the PDZ-binding motif) with GIPC (via the PDZ domain) (By similarity). Interacts with NCDN (By similarity). Interacts (via the PDZ-binding motif) with DLG4. Interacts with PLXNB2 (By similarity).
Similarity: Belongs to the semaphorin family.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Observed: 92 kDa
Predicted: 93 kDa
Predicted: 93 kDa
NCBI Official Full Name
semaphorin-4C
NCBI Official Synonym Full Names
semaphorin 4C
NCBI Official Symbol
SEMA4C
NCBI Official Synonym Symbols
SEMAF; SEMAI; SEMACL1; M-SEMA-F
NCBI Protein Information
semaphorin-4C
UniProt Protein Name
Semaphorin-4C
Protein Family
UniProt Gene Name
SEMA4C
UniProt Synonym Gene Names
KIAA1739; SEMAI
Uniprot Description
Cell surface receptor for PLXNB2 that plays an important role in cell-cell signaling. PLXNB2 binding promotes downstream activation of RHOA and phosphorylation of ERBB2 at 'Tyr-1248'. Required for normal brain development, axon guidance and cell migration (). Probable signaling receptor which may play a role in myogenic differentiation through activation of the stress-activated MAPK cascade.
Research Articles on SEMA4C
Similar Products
Product Notes
The SEMA4C sema4c (Catalog #AAA9608929) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SEMA4C Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SEMA4C can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:1000-3000. Researchers should empirically determine the suitability of the SEMA4C sema4c for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SEMA4C, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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