Rabbit anti-Human Secretin Polyclonal Antibody | anti-SCT antibody

Secretin Rabbit Polyclonal

Cat. Num. AAA7603929

• Reactivity: Human
• Applications: ELISA, Immunohistochemistry
• Purity: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Synonyms: Secretin; Polyclonal Antibody; Secretin Rabbit Polyclonal; anti-SCT antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Form/Format: Liquid
• Sequence Length: 121

• Applicable Applications for anti-SCT antibody: ELISA (EIA), Immunohistochemistry (IHC)
• Immunogen: Secretin
• Preparation and Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human stomach tissue using MBS7603929 (Secretin antibody) at dilution of 1:50)

NCBI and Uniprot Product Information

• NCBI GI #: 11345450
• NCBI GeneID: 6343
• NCBI Accession #: NP_068739.1
• NCBI GenBank Nucleotide #: NM_021920.3
• Molecular Weight: 13,016 Da
• NCBI Official Full Name: secretin preproprotein
• NCBI Official Synonym Full Names: secretin
• NCBI Official Symbol: SCT
• NCBI Protein Information: secretin
• UniProt Protein Name: Secretin
• Protein Family: Secretin
• UniProt Gene Name: SCT
• UniProt Entry Name: SECR_HUMAN

NCBI Description

This gene encodes a member of the glucagon family of peptides. The encoded preproprotein is secreted by endocrine S cells in the proximal small intestinal mucosa as a prohormone, then proteolytically processed to generate the mature peptide hormone. The release of this active peptide hormone is stimulated by either fatty acids or acidic pH in the duodenum. This hormone stimulates the secretion of bile and bicarbonate in the duodenum, pancreatic and biliary ducts. [provided by RefSeq, Feb 2016]

Uniprot Description

SCT: Stimulates formation of NaHCO(3)-rich pancreatic juice and secretion of NaHCO(3)-rich bile and inhibits HCl production by the stomach. Belongs to the glucagon family.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 11p15.5

Cellular Component: extracellular region; extracellular space

Molecular Function: hormone activity; protein N-terminus binding

Biological Process: brain development; embryonic gut development; pancreatic juice secretion; positive regulation of cAMP biosynthetic process