Immunohistochemistry (IHC)
(Immunochemical staining of human SEC14L1 in human kidney with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.)
Rabbit anti-Human SEC14L1 Polyclonal Antibody | anti-SEC14L1 antibody
Anti-SEC14L1 Antibody, Rabbit Polyclonal
Reactivity
Human
Applications
Immunohistochemistry
Purity
Protein A & Antigen Affinity
Synonyms
SEC14L1; Polyclonal Antibody; Anti-SEC14L1 Antibody; Rabbit Polyclonal; SEC14L1 Antibody; Rabbit PAb; Antigen Affinity Purified; SEC14 like lipid binding 1; Anti-PRELID4A Antibody; Anti-SEC14L Antibody; anti-SEC14L1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
Human SEC14L1
Purity/Purification
Protein A & Antigen Affinity
Form/Format
Liquid; PBS, pH7.0 with 0.03% Proclin300
Applicable Applications for anti-SEC14L1 antibody
Immunohistochemistry-Paraffin (IHC-P)
Application Notes
IHC-P: 1:50-1:200
Immunogen
E Coli-derived Human SEC14L1 fragment
Conjugation
Unconjugated
Preparation
Produced in rabbits immunized with E Coli-derived Human SEC14L1 fragment, and purified by antigen affinity chromatography.
Preparation and Storage
This antibody can be stored at 2-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Avoid repeated freeze-thaw cycles.
Immunohistochemistry (IHC)
(Immunochemical staining of human SEC14L1 in human kidney with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.)
Immunohistochemistry (IHC)
(Immunochemical staining of human SEC14L1 in human kidney with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.)
Immunohistochemistry (IHC)
(Immunochemical staining of human SEC14L1 in human testis with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.)
Immunohistochemistry (IHC)
(Immunochemical staining of human SEC14L1 in human testis with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.)
Related Product Information for anti-SEC14L1 antibody
Human Saccharomyces cerevisiae-like 1 (SEC14L1), located on chromosome 17q25, shows partial sequence homology to the budding yeast SEC14 protein and the Japanese flying squid retinal-binding protein. SEC14L1, a SEC14 family member, is a RIG-I-associated negative regulator. SEC14L1 functions as a novel negative regulator of RIG-I-mediated antiviral signaling by preventing RIG-I interaction with the downstream effector. The cytosolic factor SEC14L1 is a regulator of lipid metabolism and signaling pathways that plays a role in cancer. SEC14L1 is one of the most significant genes associated with lymphovascular invasion. SEC14L1 is an independent prognostic factor in breast cancer. Its association, at both transcriptome and protein expression levels, with lymphovascular invasion and outcome could imply an important role in tumor progression.
References
Li MT, et al. (2013) Negative regulation of rig-i-mediated innate antiviral signaling by sec14l1. J Virol 87 (18): 10037-10046.Kalikin LM, et al. (2001) Genomic characterization of human sec14l1 splice variants within a 17q25 candidate tumor suppressor gene region and identification of an unrelated embedded expressed sequence tag. Mamm Genome 12 (12): 925-929.Burdelski C, et al. (2015) Saccharomyces cerevisiae-like 1 overexpression is frequent in prostate cancer and has markedly different effects in ets-related gene fusion-positive and fusion-negative cancers. Hum Pathol 46 (4): 514-523.
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Product Notes
The SEC14L1 (Catalog #AAA8108863) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-SEC14L1 Antibody, Rabbit Polyclonal reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SEC14L1 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry-Paraffin (IHC-P). IHC-P: 1:50-1:200. Researchers should empirically determine the suitability of the SEC14L1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SEC14L1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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