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Immunohistochemistry (IHC) (Anti-SDR / SDPR antibody IHC staining of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.)

Rabbit anti-Human SDR / SDPR Polyclonal Antibody | anti-SDR antibody

Rabbit Polyclonal (IgG) to Human SDR / SDPR

Gene Names
SDPR; SDR; CAVIN2; PS-p68; cavin-2
Reactivity
Human
Applications
Immunohistochemistry, Immunofluorescence, Western Blot, ELISA
Purity
Immunoaffinity Purified
Synonyms
SDR / SDPR; Polyclonal Antibody; Rabbit Polyclonal (IgG) to Human SDR / SDPR; Anti-SDR / SDPR Antibody (N-Terminus) IHC-plus; SDPR; Cavin-2; CAVIN2; PS-p68; SDR; Serum deprivation response; Human SDR; anti-SDR antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
It is predicted to not cross-react with other members of the cavin family.
Purity/Purification
Immunoaffinity Purified
Form/Format
PBS, 0.02% sodium azide.
Concentration
1 mg/ml (varies by lot)
Sequence Length
425
Applicable Applications for anti-SDR antibody
Immunohistochemistry (IHC - Paraffin), Immunofluorescence (IF), Western Blot (WB), ELISA (EIA)
Application Notes
ELISA, IF (20 ug/ml), IHC-P (10 ug/ml), WB (1 - 2 ug/ml)
Target Species
Human
Immunogen Description
18 amino acid peptide near the amino terminus of human SDPR.
Immunogen
SDR / SDPR antibody was raised against 18 amino acid peptide near the amino terminus of human SDPR.
Antigen Modification
N-Terminus
Preparation and Storage
Long term: -20 degree C; Short term: +4 degree C. Avoid repeat freeze-thaw cycles.

Immunohistochemistry (IHC)

(Anti-SDR / SDPR antibody IHC staining of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.)

Immunohistochemistry (IHC) (Anti-SDR / SDPR antibody IHC staining of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.)

Immunofluorescence (IF)

(Immunofluorescence of SDPR in human spleen tissue with SDPR antibody at 20 ug/ml.)

Immunofluorescence (IF) (Immunofluorescence of SDPR in human spleen tissue with SDPR antibody at 20 ug/ml.)

Western Blot (WB)

(Western blot analysis of SDPR in HeLa cell lysate with SDPR antibody at (A) 1 and (B) 2 ug/ml)

Western Blot (WB) (Western blot analysis of SDPR in HeLa cell lysate with SDPR antibody at (A) 1 and (B) 2 ug/ml)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
47,173 Da
NCBI Official Full Name
serum deprivation-response protein
NCBI Official Synonym Full Names
serum deprivation response
NCBI Official Symbol
SDPR
NCBI Official Synonym Symbols
SDR; CAVIN2; PS-p68; cavin-2
NCBI Protein Information
serum deprivation-response protein; SDPR; phosphatidylserine binding protein; phosphatidylserine-binding protein
UniProt Protein Name
Serum deprivation-response protein
Protein Family
UniProt Gene Name
SDPR
UniProt Entry Name
SDPR_HUMAN

NCBI Description

This gene encodes a calcium-independent phospholipid-binding protein whose expression increases in serum-starved cells. This protein is a substrate for protein kinase C (PKC) phosphorylation and recruits polymerase I and transcript release factor (PTRF) to caveolae. Removal of this protein causes caveolae loss and its over-expression results in caveolae deformation and membrane tubulation.[provided by RefSeq, Sep 2009]

Uniprot Description

SDPR: May play a role in targeting PRKCA to caveolae. Belongs to the PTRF/SDPR family.

Protein type: Lipid-binding

Chromosomal Location of Human Ortholog: 2q32-q33

Cellular Component: cytoplasm; caveola; cytosol

Molecular Function: protein binding; protein kinase C binding; phosphatidylserine binding; phospholipid binding

Research Articles on SDR

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Product Notes

The SDR sdpr (Catalog #AAA248059) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal (IgG) to Human SDR / SDPR reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SDR / SDPR can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin), Immunofluorescence (IF), Western Blot (WB), ELISA (EIA). ELISA, IF (20 ug/ml), IHC-P (10 ug/ml), WB (1 - 2 ug/ml). Researchers should empirically determine the suitability of the SDR sdpr for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SDR / SDPR, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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