Rabbit anti-Human SDPR Polyclonal Antibody | anti-SDPR antibody

SDPR (Serum Deprivation-response Protein, CAVIN2, Cavin-2, PS-p68, Phosphatidylserine-binding Protein, SDR) (FITC)

Cat. Num. AAA6393500

• Gene Names: SDPR; SDR; CAVIN2; PS-p68; cavin-2
• Reactivity: Human
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: SDPR; Polyclonal Antibody; SDPR (Serum Deprivation-response Protein; CAVIN2; Cavin-2; PS-p68; Phosphatidylserine-binding Protein; SDR) (FITC); anti-SDPR antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human SDPR.
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein Isothiocyanate (FITC).

• Applicable Applications for anti-SDPR antibody: Western Blot (WB)
• Application Notes: Applications are based on unconjugated antibody.
• Immunogen: Full length human SDPR, aa1-425 (NP_004648).
• Immunogen Sequence: MGEDAAQAEKFQHPGSDMRQEKPSSPSPMPSSTPSPSLNLGNTEEAIRDNSQVNAVTVLTLLDKLVNMLDAVQENQHKMEQRQISLEGSVKGIQNDLTKLSKYQASTSNTVSKLLEKSRKVSAHTRAVKERMDRQCAQVKRLENNHAQLLRRNHFKVLIFQEENEIPASVFVKQPVSGAVEGKEELPDENKSLEETLHTVDLSSDDDLPHDEEALEDSAEEKVEESRAEKIKRSSLKKVDSLKKAFSRQNIEKKMNKLGTKIVSVERREKIKKSLTSNHQKISSGKSSPFKVSPLTFGRKKVREGESHAENETKSEDLPSSEQMPNDQEEESFAEGHSEASLASALVEGEIAEEAAEKATSRGSNSGMDSNIDLTIVEDEEEESVALEQAQKVRYEGSYALTSEEAERSDGDPVQPAVLQVHQTS
• Conjugate: FITC
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(Western Blot analysis of SDPR expression in transfected 293T cell line by SDPR polyclonal antibody. Lane 1: SDPR transfected lysate (47.2kD). Lane 2: Non-transfected lysate.)

Product Categories/Family for anti-SDPR antibody

Antibodies; Binding Proteins

NCBI and Uniprot Product Information

• NCBI GI #: 4759082
• NCBI GeneID: 8436
• NCBI Accession #: NP_004648.1
• NCBI GenBank Nucleotide #: NM_004657
• UniProt Accession #: O95810
• Molecular Weight: 47,173 Da
• NCBI Official Full Name: serum deprivation-response protein
• NCBI Official Synonym Full Names: serum deprivation response
• NCBI Official Symbol: SDPR
• NCBI Official Synonym Symbols: SDR; CAVIN2; PS-p68; cavin-2
• NCBI Protein Information: serum deprivation-response protein; SDPR; phosphatidylserine binding protein; phosphatidylserine-binding protein
• UniProt Protein Name: Serum deprivation-response protein
• Protein Family: Serum deprivation-response protein
• UniProt Gene Name: SDPR
• UniProt Entry Name: SDPR_HUMAN

NCBI Description

This gene encodes a calcium-independent phospholipid-binding protein whose expression increases in serum-starved cells. This protein is a substrate for protein kinase C (PKC) phosphorylation and recruits polymerase I and transcript release factor (PTRF) to caveolae. Removal of this protein causes caveolae loss and its over-expression results in caveolae deformation and membrane tubulation.[provided by RefSeq, Sep 2009]

Uniprot Description

SDPR: May play a role in targeting PRKCA to caveolae. Belongs to the PTRF/SDPR family.

Protein type: Lipid-binding

Chromosomal Location of Human Ortholog: 2q32-q33

Cellular Component: cytoplasm; caveola; cytosol

Molecular Function: protein binding; protein kinase C binding; phosphatidylserine binding; phospholipid binding