Rabbit anti-Mouse, Rat SCNN1B Polyclonal Antibody | anti-SCNN1B antibody
SCNN1B (Sodium channel, nonvoltage-gated, type I, beta Amiloride-sensitive sodium channel subunit beta, Beta-ENaC, Beta-NaCH, Epithelial Na(+) channel subunit beta, Nonvoltage-gated sodium channel 1 subunit beta, SCNEB)
Reactivity
Mouse, Rat
Applications
Western Blot, Immunohistochemistry
Purity
SerumSerum
Synonyms
SCNN1B; Polyclonal Antibody; SCNN1B (Sodium channel; nonvoltage-gated; type I; beta Amiloride-sensitive sodium channel subunit beta; Beta-ENaC; Beta-NaCH; Epithelial Na(+) channel subunit beta; Nonvoltage-gated sodium channel 1 subunit beta; SCNEB); Anti -SCNN1B (Sodium channel; anti-SCNN1B antibody
Host
Rabbit
Reactivity
Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes rat Scnn1b. Species Crossreactivity: Mouse
Purity/Purification
Serum
Serum
Serum
Form/Format
Supplied as a liquid, 50% glycerol.
Applicable Applications for anti-SCNN1B antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
Suitable for use in Western Blot and Immunohistochemistry.
Dilution: Western Blot: 1:1000
Dilution: Western Blot: 1:1000
Immunogen
Synthetic peptide corresponding to aa617-638 of the C-terminal tail of rat Scnn1b.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Related Product Information for anti-SCNN1B antibody
The Epithelial Sodium Channel (ENaC) is a membrane ion channel permeable to Na+ ions. It is located in the apical plasma membrane of epithelia in the kidneys, lung, colon, and other tissues where it plays a role in transepithelial Na+-ion transport (1). Specifically Na+ transport via ENaC occurs across many epithelial surfaces, and plays a key role in regulating salt and water absorption (2). ENaCs are composed of three structurally related subunits that form a tetrameric channel, a, B, and y. The expression of its alpha and beta subunits is enhanced as keratinocytes differentiate (3, 4). The beta and gamma-ENaC subunits are essential for edema fluid to exert its maximal effect on net fluid absorption by distal lung epithelia(5). And it has been concluded that the subunits are differentially expressed in the retina of mice with ocular hypertension, therefore the up-regulation of alpha-sodium channel proteins could serve as a protection mechanism against elevated intraocular pressure (6).
Product Categories/Family for anti-SCNN1B antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Official Full Name
sodium channel, nonvoltage-gated 1, beta
NCBI Official Symbol
SCNN1B
NCBI Protein Information
amiloride-sensitive sodium channel subunit beta; sodium channel, nonvoltage-gated 1, beta (Liddle syndrome)
Protein Family
Similar Products
Product Notes
The SCNN1B (Catalog #AAA620822) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SCNN1B (Sodium channel, nonvoltage-gated, type I, beta Amiloride-sensitive sodium channel subunit beta, Beta-ENaC, Beta-NaCH, Epithelial Na(+) channel subunit beta, Nonvoltage-gated sodium channel 1 subunit beta, SCNEB) reacts with Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's SCNN1B can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). Suitable for use in Western Blot and Immunohistochemistry. Dilution: Western Blot: 1:1000. Researchers should empirically determine the suitability of the SCNN1B for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SCNN1B, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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