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Rabbit anti-Human, Rat SCLT1 Polyclonal Antibody | anti-SCLT1 antibody

SCLT1 Antibody

Gene Names
SCLT1; CAP1A; CAP-1A; hCAP-1A
Reactivity
Human, Rat
Applications
ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Synonyms
SCLT1; Polyclonal Antibody; SCLT1 Antibody; CAP-1A; CAP1A; FLJ30655; hCAP-1A; SAP1; SCLT1_HUMAN; Sodium channel and clathrin linker 1; Sodium channel-associated protein 1; anti-SCLT1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Rat
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
SCLT1 Antibody detects endogenous levels of total SCLT1.
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Form/Format
Liquid. Rabbit IgG in phosphate buffered saline, pH7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Applicable Applications for anti-SCLT1 antibody
ELISA (EIA)(peptide)
Application Notes
ELISA(peptide): 1:20000-1:40000
Immunogen
A synthesized peptide derived from Human MYOCD.
Conjugation
Unconjugated
Subunit Structure
Interacts with SCN10A and clathrin. Identified in a complex containing SCN10A, clathrin and SCLT1 (By similarity).
Function
Adapter protein that links SCN10A to clathrin. Regulates SCN10A channel activity, possibly by promoting channel internalization (By similarity).
Note
Localizes to the distal appendage region of the centriole, which anchors the mother centriole to the plasma membrane.
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
Product Categories/Family for anti-SCLT1 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
80,910 Da
NCBI Official Full Name
SCLT1 protein
NCBI Official Synonym Full Names
sodium channel and clathrin linker 1
NCBI Official Symbol
SCLT1
NCBI Official Synonym Symbols
CAP1A; CAP-1A; hCAP-1A
NCBI Protein Information
sodium channel and clathrin linker 1; sodium channel-associated protein 1
UniProt Protein Name
Sodium channel and clathrin linker 1
UniProt Gene Name
SCLT1
UniProt Synonym Gene Names
SAP1
UniProt Entry Name
SCLT1_HUMAN

NCBI Description

SCLT1 acts as a linker protein between the voltage-gated sodium channel Na(v)1.8 (SCN10A; MIM 604427) and clathrin (see CLTC, MIM 118955) (Liu et al., 2005 [PubMed 15797711]).[supplied by OMIM, Mar 2008]

Uniprot Description

SCLT1: Adapter protein that links SCN10A to clathrin. Regulates SCN10A channel activity, possibly by promoting channel internalization. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 4q28.2

Cellular Component: centriole; centrosome; cytosol

Molecular Function: protein C-terminus binding; clathrin binding; sodium channel regulator activity

Biological Process: clustering of voltage-gated sodium channels; organelle organization and biogenesis; cilium biogenesis

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Product Notes

The SCLT1 sclt1 (Catalog #AAA9629576) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SCLT1 Antibody reacts with Human, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's SCLT1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA)(peptide). ELISA(peptide): 1:20000-1:40000. Researchers should empirically determine the suitability of the SCLT1 sclt1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SCLT1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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