Rabbit anti-Human SCHIP1 Polyclonal Antibody | anti-SCHIP1 antibody

SCHIP1, ID (SCHIP1, Schwannomin-interacting protein 1) (Biotin)

Cat. Num. AAA6345296

• Gene Names: SCHIP1; SCHIP-1
• Reactivity: Human
• Applications: Flow Cytometry, Functional Assay, ELISA, Immunohistochemistry, Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: SCHIP1; Polyclonal Antibody; ID (SCHIP1; Schwannomin-interacting protein 1) (Biotin); Schwannomin-interacting protein 1; anti-SCHIP1 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.
• Sequence Length: 487

• Applicable Applications for anti-SCHIP1 antibody: Flow Cytometry (FC/FACS), ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB)
• Application Notes: FC/FACS: 1:10-50; ELISA: 1:1,000; IHC: 1:10-50; WB: 1:100-500; Applications are based on unconjugated antibody.
• Immunogen: SCHIP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 97-126 amino acids from the Central region of human SCHIP1.
• Conjugate: Biotin
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(SCHIP1 Antibody (Center) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the SCHIP1 antibody detected the SCHIP1 protein (arrow).)

Immunohistochemistry (IHC)

(SCHIP1 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human cerebellum tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of SCHIP1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)

Flow Cytometry (FC/FACS)

(SCHIP1 Antibody (Center) flow cytometric analysis of Hela cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)

Related Product Information for anti-SCHIP1 antibody

SCHIP1 is a novel coiled-coil protein that specifically associates with schwannomin in vitro and in vivo. Within its coiled-coil region, this protein is homologous to human FEZ proteins and the related Caenorhabditis elegans gene product UNC-76.

Product Categories/Family for anti-SCHIP1 antibody

Antibodies; Proteins

References

Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010). Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010): Dubois, P.C., et al. Nat. Genet. 42(4):295-302(2010). Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009). De Jager, P.L., et al. Nat. Genet. 41(7):776-782(2009).

NCBI and Uniprot Product Information

• NCBI GI #: 7657540
• NCBI GeneID: 29970
• NCBI Accession #: NP_055390.1
• NCBI GenBank Nucleotide #: NP_055390.1
• UniProt Accession #: Q9P0W5; P0DPB3
• NCBI Official Full Name: schwannomin-interacting protein 1 isoform 1
• NCBI Official Synonym Full Names: schwannomin interacting protein 1
• NCBI Official Symbol: SCHIP1
• NCBI Official Synonym Symbols: SCHIP-1
• NCBI Protein Information: schwannomin-interacting protein 1
• UniProt Protein Name: Schwannomin-interacting protein 1
• Protein Family: Schwannomin-interacting protein
• UniProt Gene Name: SCHIP1
• UniProt Synonym Gene Names: SCHIP-1
• UniProt Entry Name: SCHI1_HUMAN

Uniprot Description

SCHIP1: 6 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 3q25.32-q25.33

Cellular Component: cytoplasm

Molecular Function: identical protein binding; protein binding