Rabbit anti-Human SAMM50 Polyclonal Antibody | anti-SAMM50 antibody

SAMM50, ID (SAMM50, Sorting and assembly machinery component 50 homolog, Transformation-related gene 3 protein)

Cat. Num. AAA643939

• Gene Names: SAMM50; OMP85; SAM50; TOB55; TRG-3; CGI-51; YNL026W
• Reactivity: Human
• Applications: ELISA, Western Blot
• Purity: Affinity Purified; Purified by Protein A affinity chromatography.
• Synonyms: SAMM50; Polyclonal Antibody; ID (SAMM50; Sorting and assembly machinery component 50 homolog; Transformation-related gene 3 protein); Anti -SAMM50; anti-SAMM50 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Human
• Purity/Purification: Affinity Purified; Purified by Protein A affinity chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

• Applicable Applications for anti-SAMM50 antibody: ELISA (EL/EIA), Western Blot (WB)
• Application Notes: Suitable for use in Western Blot, ELISA; Dilution: ELISA: 1:1,000; Western Blot: 1:100-500
• Immunogen: SAMM50 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 162-189 amino acids from the Central region of human SAMM50.
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(SAMM50 Antibody (Center) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the SAMM50 antibody detected the SAMM50 protein (arrow).)

Related Product Information for anti-SAMM50 antibody

SAMM50 is a component of the sorting and assembly machinery (SAM) complex of the outer mitochondrial membrane. The SAM complex has a role in integrating beta-barrel proteins into the outer mitochondrial membrane (Humphries et al., 2005 [PubMed 15644312]).

Product Categories/Family for anti-SAMM50 antibody

Antibodies; Abs to Mitochondrial Proteins

NCBI and Uniprot Product Information

• NCBI GI #: 225543166
• NCBI GeneID: 25813
• NCBI Accession #: NP_056195.3
• NCBI GenBank Nucleotide #: NM_015380.4
• UniProt Accession #: Q9Y512; Q53HC4; Q56VW7; Q969Y9; Q96I46; Q9NW85; Q9UQM9
• Molecular Weight: 51,976 Da
• NCBI Official Full Name: sorting and assembly machinery component 50 homolog
• NCBI Official Synonym Full Names: SAMM50 sorting and assembly machinery component
• NCBI Official Symbol: SAMM50
• NCBI Official Synonym Symbols: OMP85; SAM50; TOB55; TRG-3; CGI-51; YNL026W
• NCBI Protein Information: sorting and assembly machinery component 50 homolog; sorting and assembly machinery 50kDa; transformation-related gene 3 protein
• UniProt Protein Name: Sorting and assembly machinery component 50 homolog
• Protein Family: Sorting and assembly machinery component
• UniProt Gene Name: SAMM50
• UniProt Synonym Gene Names: TRG-3
• UniProt Entry Name: SAM50_HUMAN

NCBI Description

This gene encodes a component of the Sorting and Assembly Machinery (SAM) of the mitochondrial outer membrane. The Sam complex functions in the assembly of beta-barrel proteins into the outer mitochondrial membrane.[provided by RefSeq, Jun 2011]

Uniprot Description

SAMM50: May be required for the assembly pathway of mitochondrial outer membrane proteins. Belongs to the SAM50/omp85 family.

Protein type: Mitochondrial; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 22q13.31

Cellular Component: mitochondrial outer membrane; mitochondrion; mitochondrial inner membrane; integral to membrane

Molecular Function: protein binding

Biological Process: cellular protein metabolic process; protein targeting to mitochondrion; protein import into mitochondrial outer membrane